RENT2/UPF2 Produits
(UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
Catégories
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene\\\\; both variants encode the same protein. [provided by RefSeq, Jul 2008].
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Catégories RENT2/UPF2 en vedette
RENT2/UPF2 Anticorps
High quality antibodies with extensive validation data.
RENT2/UPF2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
N° du produit
ABIN6149941
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS
Validations
- (2)
N° du produit
ABIN654649
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN6570914
Quantité
200 μL
Fiche technique
Fiche technique
RENT2/UPF2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3095007
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2735035
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits RENT2/UPF2
: "Compound C inhibits nonsense-mediated RNA decay independently of AMPK." dans: PLoS ONE, Vol. 13, Issue 10, pp. e0204978, (2019) (PubMed).: "Intracellular calcium regulates nonsense-mediated mRNA decay." dans: Nature medicine, Vol. 20, Issue 8, pp. 961-6, (2014) (PubMed).
: "CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells." dans: Nature structural & molecular biology, Vol. 12, Issue 10, pp. 893-901, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à RENT2/UPF2
UPF2, regulator of nonsense mediated mRNA decay (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (Upf2), UPF2, regulator of nonsense mediated mRNA decay (Upf2), UPF2 regulator of nonsense transcripts homolog (yeast) (UPF2), UPF2 regulator of nonsense transcripts homolog (yeast) (upf2), HUPF2, RENT2, smg-3Protein level used designations for RENT2/UPF2
- nonsense mRNA reducing factor 2
- regulator of nonsense transcripts 2
- smg-3 homolog, nonsense mediated mRNA decay factor
- up-frameshift suppressor 2 homolog
- yeast Upf2p homolog
- UPF2 regulator of nonsense transcripts homolog (yeast)
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