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REST Produits

(RE1-Silencing Transcription Factor (REST))
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq, Jul 2010].

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Catégories REST en vedette

REST Anticorps

High quality antibodies with extensive validation data.

REST Kits ELISA

Reliable ELISA kits for a wide range of species.

REST Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

REST recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
  • (6)
N° du produit ABIN747683
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
  • (6)
N° du produit ABIN2779670
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (3)
N° du produit ABIN7269883
Quantité 100 μL
Fiche technique Fiche technique

REST recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6975568
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969840
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6235985
Quantité 96 tests
Fiche technique Fiche technique

REST recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3136764
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3095008
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2751253
Quantité 5 applications
Fiche technique Fiche technique

Dernières publications sur nos produits REST

Li, Cheng, Xu, Zhang, Tokat, Dolios, Ramakrishnan, Shen, Wang, Xu: "The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity." dans: Nucleic acids research, Vol. 50, Issue 18, pp. 10343-10359, (2022) (PubMed).

Li, Liu, Wu, Chen, Wang, Wang, Huang, Wang, Yu, Fei, Huang: "The deficiency of NRSF/REST enhances the pro-inflammatory function of astrocytes in a model of Parkinson's disease." dans: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1866, Issue 1, pp. 165590, (2020) (PubMed).

Ashton, Hye, Leckey, Jones, Gardner, Elliott, Wetherell, Lenze, Killick, Marchant: "Plasma REST: a novel candidate biomarker of Alzheimer's disease is modified by psychological intervention in an at-risk population." dans: Translational psychiatry, Vol. 7, Issue 6, pp. e1148, (2018) (PubMed).

Lu, Tran, Park, Chen, Lan, Xie, Semenza: "Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment." dans: Cancer research, Vol. 78, Issue 15, pp. 4191-4202, (2018) (PubMed).

Zhang, Wang, Lu, Wang, Yuan, Yan, Cai, Chang, Zheng, Wu, Zhou: "REST regulates the cell cycle for cardiac development and regeneration." dans: Nature communications, Vol. 8, Issue 1, pp. 1979, (2018) (PubMed).

Zhang, Wu, Wang, Wang, Lu, Nechiporuk, Floss, Greally, Zheng, Zhou: "Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts." dans: Nucleic acids research, Vol. 45, Issue 6, pp. 3102-3115, (2017) (PubMed).

Perera, Eisen, Wagner, Laube, Künzel, Koch, Steinbacher, Schulze, Splith, Mittermeier, Müller, Biel, Carell, Michalakis: "TET3 is recruited by REST for context-specific hydroxymethylation and induction of gene expression." dans: Cell reports, Vol. 11, Issue 2, pp. 283-94, (2015) (PubMed).

Mehta, Kim, Vemuganti: "Long Noncoding RNA FosDT Promotes Ischemic Brain Injury by Interacting with REST-Associated Chromatin-Modifying Proteins." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 50, pp. 16443-9, (2015) (PubMed).

Kashiwagi, Ishii, Sakaeda, Arimasu, Shimoyamada, Sato, Miyata, Kamma, Aoki, Yazawa: "Differences of molecular expression mechanisms among neural cell adhesion molecule 1, synaptophysin, and chromogranin A in lung cancer cells." dans: Pathology international, Vol. 62, Issue 4, pp. 232-45, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à REST

RE1 silencing transcription factor (REST), RE1-silencing transcription factor (Rest), RE1-silencing transcription factor S homeolog (rest.S), RE1-silencing transcription factor (REST), RE1-silencing transcription factor (rest), RE1-silencing transcription factor (LOC615792), RE1 silencing transcription factor (rest), 2610008J04Rik, AA407358, NRSF, nrsf, rest, REST, resta, XBR, xbr

Protein level used designations for REST

  • neural-restrictive silencer factor
  • neuron restrictive silencer factor
  • repressor binding to the X2 box
  • zinc finger transcription factor REST protein
  • RE1-silencing transcription factor B
  • RE1-silencing transcription factor a
  • neural-restrictive silencer factor B
  • RE1-silencing transcription factor
  • RE-1 silencer of transcription
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