This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010].
RETN
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Dernières publications pour nos Resistin Protéines
Nakayama, Aoki, Uchihashi, Nishijima-Matsunobu, Yamamoto, Kakihara, Iwakiri, Fujimoto, Toda: "Interaction between Esophageal Squamous Cell Carcinoma and Adipose Tissue in Vitro." dans: The American journal of pathology, Vol. 186, Issue 5, pp. 1180-94, (2016) (PubMed).
Daquinag, Zhang, Amaya-Manzanares, Simmons, Kolonin: "An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." dans: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).
Takata, Osawa, Kurata, Kurokawa, Yamauchi, Ochi, Nishida, Okura, Higaki, Makino: "Hyperresistinemia is associated with coexistence of hypertension and type 2 diabetes." dans: Hypertension, Vol. 51, Issue 2, pp. 534-9, (2008) (PubMed).
Shen, Zhang, Gan, Wang, Wang, LeMaire, Coselli, Wang et al.: "Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and ..." dans: The Journal of biological chemistry, Vol. 281, Issue 12, pp. 7727-36, (2006) (PubMed).