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RFFL Produits

(Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

Catégories

Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.

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Catégories RFFL en vedette

RFFL Anticorps

High quality antibodies with extensive validation data.

RFFL Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RFFL recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (4)
N° du produit ABIN566759
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7151117
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (5)
  • (1)
N° du produit ABIN1881744
Quantité 400 μL
Fiche technique Fiche technique

RFFL recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6221029
Quantité 96 tests
Fiche technique Fiche technique

RFFL recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317849
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1317851
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3135886
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RFFL

Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." dans: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." dans: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

Newton-Cheh, Eijgelsheim, Rice, de Bakker, Yin, Estrada, Bis, Marciante, Rivadeneira, Noseworthy, Sotoodehnia, Smith, Rotter, Kors, Witteman, Hofman, Heckbert: "Common variants at ten loci influence QT interval duration in the QTGEN Study." dans: Nature genetics, Vol. 41, Issue 4, pp. 399-406, (2009) (PubMed).

Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." dans: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).

Liao, Xiao, Tchikov, Fujita, Yang, Wincovitch, Garfield, Conze, El-Deiry, Schütze, Srinivasula: "CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation." dans: Current biology : CB, Vol. 18, Issue 9, pp. 641-9, (2008) (PubMed).

Yang, Dicker, Chen, El-Deiry: "CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2." dans: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 5, pp. 670-82, (2008) (PubMed).

McDonald, El-Deiry: "Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 16, pp. 6170-5, (2004) (PubMed).

Coumailleau, Das, Alcover, Raposo, Vandormael-Pournin, Le Bras, Baldacci, Dautry-Varsat, Babinet, Cohen-Tannoudji: "Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment." dans: Molecular biology of the cell, Vol. 15, Issue 10, pp. 4444-56, (2004) (PubMed).

Tibbetts, Shiozaki, Gu, McDonald, El-Deiry, Shi: "Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2." dans: Structure (London, England : 1993), Vol. 12, Issue 12, pp. 2257-63, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à RFFL

ring finger and FYVE like domain containing E3 ubiquitin protein ligase (RFFL), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog (rffl.L), ring finger and FYVE-like domain containing 1 (Rffl), ring finger and FYVE like domain containing protein (Rffl), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl), 1700051E09Rik, 4930516L10Rik, BG080975, CARP-2, Carp2, CARP2, FRING, MGC84042, RFFL, Rffl, RIFIFYLIN, RNF34L, RNF189

Protein level used designations for RFFL

  • E3 ubiquitin-protein ligase rififylin
  • ring finger and FYVE-like domain containing 1
  • rififylin
  • e3 ubiquitin-protein ligase rififylin-like
  • RING finger and FYVE-like domain-containing protein 1
  • fring
  • FYVE-RING finger protein SAKURA
  • RING finger protein 189
  • caspase regulator CARP2
  • caspases-8 and -10-associated RING finger protein 2
  • FYVE-RING finger protein Sakura
  • RING finger protein SAKURA
  • ring finger and FYVE like domain containing protein
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