SCARB2 Produits
(Scavenger Receptor Class B, Member 2 (SCARB2))
Catégories
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
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Catégories SCARB2 en vedette
SCARB2 Anticorps
High quality antibodies with extensive validation data.
SCARB2 Kits ELISA
Reliable ELISA kits for a wide range of species.
SCARB2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SCARB2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7158800
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
N° du produit
ABIN873185
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN560246
Quantité
50 μL
Fiche technique
Fiche technique
SCARB2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN2703297
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1141297
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1141296
Quantité
96 tests
Fiche technique
Fiche technique
SCARB2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
N° du produit
ABIN7320637
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
N° du produit
ABIN7320638
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319219
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SCARB2
: "Endophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cells." dans: Emerging microbes & infections, Vol. 8, Issue 1, pp. 773-786, (2019) (PubMed).: "Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence." dans: Emerging microbes & infections, Vol. 8, Issue 1, pp. 1076-1085, (2019) (PubMed).
: "Age-related endolysosome dysfunction in the rat urothelium." dans: PLoS ONE, Vol. 13, Issue 6, pp. e0198817, (2018) (PubMed).
: "Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition." dans: Biochimica et biophysica acta. Molecular cell research, Vol. 1865, Issue 9, pp. 1356-1367, (2018) (PubMed).
: "Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 2, pp. 206-16, (2016) (PubMed).
: "Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC." dans: Disease models & mechanisms, Vol. 9, Issue 9, pp. 999-1013, (2016) (PubMed).
: "A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71." dans: Scientific reports, Vol. 6, pp. 31151, (2016) (PubMed).
: "Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms." dans: Human molecular genetics, Vol. 26, Issue 1, pp. 173-183, (2016) (PubMed).
: "Liver growth factor induces testicular regeneration in EDS-treated rats and increases protein levels of class B scavenger receptors." dans: American journal of physiology. Endocrinology and metabolism, Vol. 308, Issue 2, pp. E111-21, (2015) (PubMed).
: "Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis." dans: Cellular and molecular gastroenterology and hepatology, Vol. 1, Issue 6, pp. 678-694, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à SCARB2
scavenger receptor class B, member 2a (scarb2a), scavenger receptor class B member 2 (SCARB2), scavenger receptor class B member 2 (scarb2), scavenger receptor class B, member 2 (Scarb2), 9330185J12Rik, AMRF, cd36l2, CD36L2, Cd36l2, chunp6914, EPM4, fi13c07, HLGP85, LGP85, LIMP-2, LIMPII, LimpII, MLGP85, SCARB2, scarb2, SR-BII, wu:fi13c07Protein level used designations for SCARB2
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2
- CD36 antigen-like 2
- lysosome membrane protein 2
- scavenger receptor class B, member 2
- lysosome membrane protein 2-like
- putative lysosomal integral membrane protein II
- 85 kDa lysosomal membrane sialoglycoprotein
- 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
- LIMP II
- lysosome membrane protein II
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