SETD7 Protéines
(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
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custom-made
SETD7
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SETD7
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SETD7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
SETD7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SETD7
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 94 % as determined by reducing SDS-PAGE.
custom-made
SETD7
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
SETD7
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
SETD7
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
SETD7
Origine: Xenopus tropicalis
Hôte: Levure
Recombinant
> 90 %
ELISA
Pseudonymes pour SETD7 Protéines
SET domain containing lysine methyltransferase 7 (SETD7) ProtéinesSET domain containing (lysine methyltransferase) 7 (setd7) Protéines
SET domain containing (lysine methyltransferase) 7 (Setd7) Protéines
1600028F23Rik Protéines
H3K4MT Protéines
KMT7 Protéines
mKIAA1717 Protéines
SET7 Protéines
set7 Protéines
Set7 Protéines
SET7/9 Protéines
Set7/9 Protéines
SET9 Protéines
zgc:92330 Protéines
zgc:101860 Protéines
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