SETD7 Produits
(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
Catégories
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
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Catégories SETD7 en vedette
SETD7 Anticorps
High quality antibodies with extensive validation data.
SETD7 Kits ELISA
Reliable ELISA kits for a wide range of species.
SETD7 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SETD7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey, Rat
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (5)
N° du produit
ABIN7193392
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Rat
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (5)
N° du produit
ABIN7193393
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (5)
N° du produit
ABIN566461
Quantité
100 μg
Fiche technique
Fiche technique
SETD7 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959453
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951695
Quantité
96 tests
Fiche technique
Fiche technique
SETD7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN5569632
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1319680
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3136750
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits SETD7
: "Minimally invasive implantation and decreased inflammation reduce osteoinduction of biomaterial." dans: Theranostics, Vol. 10, Issue 8, pp. 3533-3545, (2021) (PubMed).: "Setd7 and its contribution to Boron-induced bone regeneration in Boron-mesoporous bioactive glass scaffolds." dans: Acta biomaterialia, Vol. 73, pp. 522-530, (2018) (PubMed).
: "SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis." dans: Cell reports, Vol. 15, Issue 12, pp. 2733-44, (2016) (PubMed).
: "Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase." dans: Molecular cell, Vol. 30, Issue 3, pp. 336-47, (2008) (PubMed).
: "Protein demethylation required for DNA methylation." dans: Nature genetics, Vol. 41, Issue 1, pp. 10-1, (2008) (PubMed).
: "The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 26, pp. 10835-40, (2007) (PubMed).
: "Regulation of p53 activity through lysine methylation." dans: Nature, Vol. 432, Issue 7015, pp. 353-60, (2004) (PubMed).
: "Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet." dans: The EMBO journal, Vol. 22, Issue 2, pp. 292-303, (2003) (PubMed).
: "Structure and catalytic mechanism of the human histone methyltransferase SET7/9." dans: Nature, Vol. 421, Issue 6923, pp. 652-6, (2003) (PubMed).
: "Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1." dans: Genes & development, Vol. 17, Issue 7, pp. 896-911, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à SETD7
SET domain containing lysine methyltransferase 7 (SETD7), SET domain containing (lysine methyltransferase) 7 (setd7), SET domain containing (lysine methyltransferase) 7 (Setd7), 1600028F23Rik, H3K4MT, KMT7, mKIAA1717, SET7, set7, Set7, SET7/9, Set7/9, SET9, zgc:92330, zgc:101860Protein level used designations for SETD7
- H3-K4-HMTase SETD7
- SET domain-containing protein 7
- histone H3-K4 methyltransferase SETD7
- histone H3-lysine 4-specific methyltransferase
- histone-lysine N-methyltransferase SETD7
- lysine N-methyltransferase 7
- H3-K4 methyltransferase
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