Recombinant Lapin anti-Humain IgD (AA 1-200), (Heavy Chain) Anticorps

N° du produit ABIN7868799

Aperçu rapide pour Recombinant Lapin anti-Humain IgD (AA 1-200), (Heavy Chain) Anticorps (ABIN7868799)

Antigène: IgD

Type d'anticorp: Recombinant Antibody

Clonalité: Monoclonal

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IGHD-8228R

Isotype: IgG, kappa

Détail du produit

Épitope: AA 1-200, Heavy Chain

Reactivité: Humain

Hôte: Lapin

Fonction: Recombinant IgD Heavy Chain Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the recombinant IgD Heavy Chain antibody.

Information d'application

Indications d'application: Optimal dilution of the recombinant IgD Heavy Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant IgD Heavy Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: IgD

Classe de substances: Antibody

Sujet: Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

UniProt: P01880