Souris anti-Humain IgD (full length), (Heavy Chain) Anticorps

N° du produit ABIN7879401

Aperçu rapide pour Souris anti-Humain IgD (full length), (Heavy Chain) Anticorps (ABIN7879401)

Antigène: IgD

Clonalité: Monoclonal

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: IGHD-4967

Isotype: IgG2a, kappa

Détail du produit

Épitope: full length, Heavy Chain

Reactivité: Humain

Hôte: Souris

Fonction: IgD Heavy Chain Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: Full-length human IGHD protein was used as the immunogen for the IgD Heavy Chain antibody.

Information d'application

Indications d'application: Optimal dilution of the IgD Heavy Chain antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the IgD Heavy Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: IgD

Classe de substances: Antibody

Sujet: Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

UniProt: P01880