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Souris anti-Humain IgG (Fd Region) Anticorps

WB, FACS, EIA Monoclonal HP6045 IgG1 unconjugated
N° du produit ABIN952843
  • Antigène Tous les produits IgG
    IgG
    Épitope
    • 2356
    • 502
    • 411
    • 188
    • 130
    • 123
    • 94
    • 29
    • 28
    • 28
    • 17
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Fd Region
    Reactivité
    • 700
    • 679
    • 570
    • 458
    • 368
    • 239
    • 200
    • 148
    • 140
    • 132
    • 122
    • 98
    • 97
    • 96
    • 94
    • 63
    • 47
    • 38
    • 27
    • 16
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 1739
    • 1486
    • 539
    • 218
    • 118
    • 103
    • 33
    • 31
    • 21
    • 17
    • 15
    • 11
    • 11
    • 1
    Souris
    Clonalité
    • 3368
    • 195
    • 1
    Monoclonal
    Application
    • 1870
    • 1797
    • 1791
    • 1536
    • 988
    • 934
    • 913
    • 515
    • 234
    • 115
    • 115
    • 110
    • 100
    • 87
    • 77
    • 52
    • 50
    • 48
    • 32
    • 27
    • 25
    • 21
    • 17
    • 16
    • 11
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human.
    Purification
    Protein G Chromatography.
    Immunogène
    Human IgG Fd
    Clone
    HP6045
    Isotype
    IgG1
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • Lebozec, Jandrot-Perrus, Avenard, Favre-Bulle, Billiald: "Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks." dans: mAbs, Vol. 9, Issue 6, pp. 945-958, (2017) (PubMed).

  • Antigène
    IgG
    Abstract
    IgG Produits
    Classe de substances
    Antibody
    Sujet
    The Fd region of Human Immunoglobulins is located at the N-terminal part of the heavy chain and is an essential component of the antigen-binding fragment Fab. Fd, like the light chain, contains a C-terminal constant (CH1) and N- terminal variable (VH) domain. The hypervariable regions in both the light chain and Fd determine the specificity of the Fab.Synonyms: Human Immunoglobulin G
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