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Anti-Human IgE Secondary Antibodies

Choose from a handpicked selection of anti-human secondary antibodies with enzymatic conjugates like AP, Biotin or HRP or fluorescent conjugates including FITC, APC and DyLight and Atto dye families. Browse our offer for a variety of different host, isotypes or binding specifities.

Browse all human IgE secondaries

Unconjugated Anti-Human IgE Secondary Antibodies

Produit
Application
N° du produit
Quantité
Application IP
N° du produit ABIN458100
Quantité 1 mL

Anti-Human IgE Secondary Antibodies with Enzymatic Conjugates

Secondary antibodies linked with enzymes such as HRP and alkaline phosphatase AP are commonly utilized in applications such as ELISA or Western blotting. Both can be detected using colorimetric or chemiluminescent readout.

Produit
Conjugué
Application
N° du produit
Quantité
Conjugué Biotin
Application ELISA
N° du produit ABIN135676
Quantité 0.5 mg
Conjugué Alkaline Phosphatase (AP)
Application ELISA, WB, IHC, ICC, IA
N° du produit ABIN336560
Quantité 1 mg
Conjugué HRP
Application ELISA, WB, IHC, IA
N° du produit ABIN400149
Quantité 1 mg

Anti-Human IgE Secondary Antibodies with Fluorescent Conjugates

Secondary antibodies conjugated to fluorescent proteins, eg FITC, TRITC, APC or PE or commercial dye families excel in flow cytometry or immunofluorescence experiments. For example the FITC conjugated Goat Anti-Rabbit IgE. DyLight flurorescent conjugates are an excellent alternative to IRDye550CW or IRDye680CW, they offer comparable excitation and emission spectra and are claimed to be more photostable.

Produit
Conjugué
Application
N° du produit
Quantité
Conjugué PE
Application FACS
N° du produit ABIN192257
Quantité 0.1 mg
Conjugué FITC
Application ELISA, FLISA
N° du produit ABIN5707454
Quantité 0.5 mg
Conjugué TRITC
Application FACS, IM
N° du produit ABIN3045755
Quantité 1 mg
Conjugué DyLight 650
Application FACS, IF
N° du produit ABIN612001
Quantité 1 mg
Conjugué DyLight 800
Application FACS, IF
N° du produit ABIN612003
Quantité 1 mg
Conjugué APC
Application FACS, CA
N° du produit ABIN1113051
Quantité 100 μg

IgE Role in Allergies

IgE that can specifically recognise an allergen (typically this is a protein, such as dust mite or ragweed pollen) has a unique interaction with its high-affinity receptor FcεRI lasting for years. IgE can upregulate the expression of both types of Fcε receptors. Basals and mast cells, capable of mediating inflammatory reactions, become "primed", ready to release messengers like histamine, leukotrienes, and certain interleukins which both help the mast cells survive and accumulate in tissue.

Atopic individuals can have up to ten times the normal level of IgE in their blood; asthmatics however show only local IgE production in the nasal mucosa. Symptoms associated with allergy are airway constriction in asthma, local inflammation in eczema, increased mucus secretion in allergic rhinitis, and increased vascular permeability, presumably to allow other immune cells to gain access to tissues, but which can lead to a potentially fatal drop in blood pressure as in anaphylaxis.

IgE in Autoimmune Disorders

IgE is known to be elevated in various autoimmune disorders such as T-cell defect, hyper IgE syndrome, SLE, rheumatoid arthritis, and psoriasis. Regulation of IgE levels through control of B cell differentiation to antibody-secreting plasma cells is thought to involve the "low-affinity" receptor FcεRII, or CD23. CD23 may also allow facilitated antigen presentation, an IgE-dependent mechanism whereby B cells expressing CD23 are able to present allergen to (and stimulate) specific T helper cells, causing the perpetuation of a Th2 response, one of the hallmarks of which is the production of more antibodies.

IgE in Medical Diagnostics

The concentration of total IgE plays a significant role in the evaluation of allergic diseases, especially eosinophilic pulmonary infiltrates, eosinophilic gastroenteritis and allergic alveolitis like farmer's lung, vasculitides such as granulomatosis with polyangiitis, Churg-Strauss syndrome, and allergic bronchopulmonary aspergillosis. IgE is also often elevated in parasitoses. IgE determination is useful in immunodeficiencies such as T-cell defect, hyper IgE syndrome or rheumatoid arthritis, but also in forms of urticaria, atopic dermatitis, in Quincke's edema, or in unclear exanthema.

Human IgE Secondaries

55 Résultats :

ELISA, FACS Monoclonal 4G7-325 IgG unconjugated
Pubmed 2 références
N° du produit ABIN94398
ELISA Monoclonal HP6029 IgG2a Biotin
Pubmed 1 reference
N° du produit ABIN135676
FACS Monoclonal BE5 IgG1 FITC
Pubmed 1 reference
N° du produit ABIN192255
FACS Monoclonal BE5 IgG1 PE
Pubmed 1 reference
N° du produit ABIN192257
ELISA, WB, IHC Monoclonal B3102E8 IgG1 HRP
Pubmed 1 reference
N° du produit ABIN135650
ELISA, WB Polyclonal IgG Alkaline Phosphatase (AP)
Pubmed 1 reference
N° du produit ABIN2474282
ELISA, WB Polyclonal IgG unconjugated
Pubmed 1 reference
N° du produit ABIN2474281
ELISA, WB Polyclonal IgG Biotin
Pubmed 1 reference
N° du produit ABIN2474283
FACS Polyclonal IgG FITC
Pubmed 1 reference
N° du produit ABIN2474284
ELISA Polyclonal IgG HRP
Pubmed 1 reference
N° du produit ABIN2474285
BCA Monoclonal MHE-18 IgG1 kappa APC
N° du produit ABIN2667008
WB Monoclonal MHE-18 IgG1 kappa PE-Cy7
N° du produit ABIN2667032
FACS Monoclonal MHE-18 IgG1 kappa PerCP-Cy5.5
N° du produit ABIN2667054
ELISA Monoclonal B3102E8 IgG1 unconjugated
N° du produit ABIN135648
ELISA, WB, IHC, ICC Polyclonal IgG unconjugated
N° du produit ABIN7446313
  • Type Secondary
    • Secondary
  • Target IgE
    • IgE
    • IgG
    • IgM
    • IgA
    • Ig
    • IgA, IgG, IgM
    • IgD
    • Igk
    • kappa Light Chain
    • IgG4
    • lambda
    • IgG1
    • IgG2
    • IgG3
    • Lambda-IgLC
    • IgA2
    • IgA1
    • Ig lambda
    • IgA Secretory Component
    • IgG Fc
    • IgG Heavy Chain (LOC396781)
    • IgH
    • IGJ
    • IgG + IgA + IgM + IgD
    • IgG, IgM
    • kappa Chain
    • lambda Chain
    • Fab
    • Fc
    • IgA1,2
    • IGHG1
    • Ig Light Chains
    • IgM Heavy Chain
    • IGHA2
    • IGHM
    • CD79a (CD79A)
    • Bence-Jones Protein kappa
    • Bence-Jones Protein lambda
    • CD79
    • GLS2
    • Ig lambda C
    • IgA + IgD + IgE + IgG + IgM
    • IgA, IgD
    • IgA3
    • IgA4
    • IgA6
    • IgAc, IgA1, IgA2
    • IgG + IgD
    • IgG lambda
    • IgG1 + IgG2 + IgG3 + IgG4
    Please use search to find more...
  • Application
    • ELISA
    • Flow Cytometry (FACS)
    • Western Blotting (WB)
    • Immunocytochemistry (ICC)
    • Immunohistochemistry (IHC)
    • Immunofluorescence (IF)
    • Immunoassay (IA)
    • Enzyme Immunoassay (EIA)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunoprecipitation (IP)
    • Cellular Assay (CA)
    • Immunomicroscopy (IM)
    • Dot Blot (DB)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Microarray (MA)
    • Biochemical Assay (BCA)
    • ELISA (Detection)
    • FLISA
    • Protein Assay (PrA)
  • Réactivité Human
    • Human
    • Mouse
    • Rat
    • Dog
    • Rhesus Monkey
    • Monkey
    • Pig
    • Cat
  • Cité dans publications
  • Images disponible
  • Preservative free only
  • Carrier free only
  • Hote
    • Goat
    • Mouse
    • Pig
    • Rabbit
    • Sheep
  • Clonalité
    • Polyclonal
    • Monoclonal
  • Clone
    • B3102E8
    • MHE-18
    • BE5
    • 4F4cc
    • 4G7-325
    • 8E-5D4
    • HP6029
    • XTE4
  • Epitope
    • Fc Region
    • Chain epsilon
    • Heavy Chain
    • Ce2 Domain
    • Chain epsilon 3
  • Conjugué
    • Inconjugué
    • FITC
    • HRP
    • Biotin
    • Alkaline Phosphatase (AP)
    • TRITC
    • APC
    • PE
    • DyLight 350
    • DyLight 488
    • DyLight 633
    • DyLight 650
    • DyLight 800
    • PE-Cy7
    • PerCP-Cy5.5
    • Rhodamine
    • SureLight® R-PE
  • Isotype
    • IgG
    • IgG1
    • IgG1 kappa
    • IgG2a
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • Acris
    • Agrisera
    • BioLegend
    • Columbia Biosciences
    • Assaypro
    • Hytest
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