SMAD4 Protéines
(SMAD Family Member 4 (SMAD4))
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009].
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custom-made
SMAD4
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
SMAD4
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SMAD4
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
SMAD4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
SMAD4
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
1 reference
SMAD4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 85 % as determined by reducing SDS-PAGE.
SMAD4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SMAD4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, PC, Imm
SMAD4
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, PC, Imm
custom-made
SMAD4
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
SMAD4
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
SMAD4
Origine: Humain, Souris, Rat
Hôte: Escherichia coli (E. coli)
Recombinant
WB, PC
Rockland 009-001-t40s
SMAD4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>80%
WB
Rockland Original
Dernières publications pour nos SMAD4 Protéines
: "M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo." dans: Translational research : the journal of laboratory and clinical medicine, Vol. 170, pp. 99-111, (2016) (PubMed).: "Transforming growth factor beta-induced reactivation of Epstein-Barr virus involves multiple Smad-binding elements cooperatively activating expression of the latent-lytic switch BZLF1 gene." dans: Journal of virology, Vol. 85, Issue 15, pp. 7836-48, (2011) (PubMed).
Pseudonymes pour SMAD4 Protéines
SMAD family member 4 (SMAD4) ProtéinesSmad4 protein (smad4) Protéines
SMAD family member 4 (Smad4) Protéines
SMAD family member 4, gene 1 L homeolog (smad4.1.L) Protéines
AW743858 Protéines
D18Wsu70e Protéines
DPC4 Protéines
dpc4 Protéines
JIP Protéines
jip Protéines
MADH4 Protéines
Madh4 Protéines
madh4 Protéines
MYHRS Protéines
smad4 Protéines
Xsmad4 Protéines
xsmad4a Protéines
XSmad4alpha Protéines
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