SNCA Produits
(Synuclein, alpha (SNCA))
Catégories
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
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Catégories SNCA en vedette
SNCA Anticorps
High quality antibodies with extensive validation data.
SNCA Kits ELISA
Reliable ELISA kits for a wide range of species.
SNCA Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
SNCA recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (7)
N° du produit
ABIN6254965
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (4)
N° du produit
ABIN6148190
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
N° du produit
ABIN5650939
Quantité
100 μL
Fiche technique
Fiche technique
SNCA recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6962177
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
N° du produit
ABIN6959829
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
N° du produit
ABIN6959830
Quantité
96 tests
Fiche technique
Fiche technique
SNCA recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (6)
N° du produit
ABIN6952303
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (9)
N° du produit
ABIN5651245
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (10)
N° du produit
ABIN5065829
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SNCA
: "Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson's disease." dans: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 393, Issue 3, pp. 429-444, (2021) (PubMed).: "Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model." dans: Molecular and cellular biochemistry, Vol. 465, Issue 1-2, pp. 89-102, (2020) (PubMed).
: "Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease." dans: International journal of pharmaceutics, Vol. 579, pp. 119148, (2020) (PubMed).
: "Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys." dans: EBioMedicine, Vol. 59, pp. 102944, (2020) (PubMed).
: "Exosomes from patients with Parkinson's disease are pathological in mice." dans: Journal of molecular medicine (Berlin, Germany), Vol. 97, Issue 9, pp. 1329-1344, (2020) (PubMed).
: "Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson's disease symptoms." dans: Biochemical pharmacology, Vol. 155, pp. 479-493, (2019) (PubMed).
: "Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin." dans: Journal of Alzheimer's disease : JAD, Vol. 69, Issue 2, pp. 463-478, (2019) (PubMed).
: "Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease." dans: Life sciences, Vol. 223, pp. 158-165, (2019) (PubMed).
: "An Enriched Environment Ameliorates Oxidative Stress and Olfactory Dysfunction in Parkinson's Disease with α-Synucleinopathy." dans: Cell transplantation, Vol. 27, Issue 5, pp. 831-839, (2019) (PubMed).
: "Apelin-36 mitigates MPTP/MPP+-induced neurotoxicity: Involvement of α-synuclein and endoplasmic reticulum stress." dans: Brain research, Vol. 1721, pp. 146334, (2019) (PubMed).
Synonymes et noms alternatifs relatifs à SNCA
synuclein alpha L homeolog (snca.L), alpha-synuclein (LOC619283), synuclein alpha (SNCA), synuclein, alpha (Snca), synuclein alpha (Snca), alphaSYN, LOC619283, MGC64356, NACP, PARK1, PARK4, PD1, sncaProtein level used designations for SNCA
- synuclein, alpha
- alpha-synuclein
- alpha SYN
- non-A beta component of AD amyloid
- non-A4 component of amyloid
- non A-beta component of AD amyloid
- synuclein alpha-140
- alpha synuclein
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