SNCA Protéines
(Synuclein, alpha (SNCA))
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009].
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MALS verified
SNCA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
95,00 %
MALS verified
SNCA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
95,00 %
SNCA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
90 %
Active
SNCA
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
SNCA
Origine: Red-chested mustached Tamarin (Saguinus labiatus)
Hôte: Levure
Recombinant
> 90 %
ELISA
SNCA
Origine: Primate (Erythrocebus)
Hôte: Levure
Recombinant
> 90 %
ELISA
SNCA
Origine: Serinus canaria
Hôte: Levure
Recombinant
> 90 %
ELISA
Dernières publications pour nos SNCA Protéines
: "Unraveling the role of hydrogen peroxide in ?-synuclein aggregation using an ultrasensitive nanoplasmonic probe." dans: Analytical chemistry, Vol. 87, Issue 3, pp. 1968-73, (2015) (PubMed).: "Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity." dans: Neuron, Vol. 46, Issue 2, pp. 233-45, (2005) (PubMed).
: "Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid." dans: Biochemical and biophysical research communications, Vol. 205, Issue 2, pp. 1366-72, (1995) (PubMed).
: "The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease." dans: Genomics, Vol. 26, Issue 2, pp. 254-7, (1995) (PubMed).
: "Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11282-6, (1994) (PubMed).
Pseudonymes pour SNCA Protéines
synuclein alpha L homeolog (snca.L) Protéinesalpha-synuclein (LOC619283) Protéines
synuclein alpha (SNCA) Protéines
synuclein, alpha (Snca) Protéines
synuclein alpha (Snca) Protéines
alphaSYN Protéines
LOC619283 Protéines
MGC64356 Protéines
NACP Protéines
PARK1 Protéines
PARK4 Protéines
PD1 Protéines
snca Protéines
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