STAT3 Protéines
(Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| STAT3 Protein (His tag) | Souris | Cellules d'insectes |
|
662,00 €
Voir le prix
|
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| STAT3 Protein (AA 1-770) (GST tag) | Souris | Bacteria |
|
302,50 €
Voir le prix
|
|
| STAT3 Protein (AA 1-770) (His tag) | Souris | Eukaryota |
|
361,90 €
Voir le prix
|
|
| STAT3 Protein (AA 1-770) (His tag) | Humain | Eukaryota |
|
361,90 €
Voir le prix
|
|
| STAT3 Protein (AA 1-770) (GST tag) | Humain | Bacteria |
|
302,50 €
Voir le prix
|
|
| STAT3 Protéine | Humain, Rat, Souris | Escherichia coli (E. coli) |
|
364,62 €
Voir le prix
|
|
| STAT3 Protein (GST tag) | Humain | Escherichia coli (E. coli) |
|
503,00 €
Voir le prix
|
|
| STAT3 Protein (His tag) | Humain | Escherichia coli (E. coli) |
|
878,90 €
Voir le prix
|
|
| STAT3 Protein (His tag) | Humain | Cellules d'insectes |
|
662,00 €
Voir le prix
|
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Souris
- Hôte
- Cellules d'insectes
- Type Proteine
- Recombinant
Protein
- WB (Western Blotting: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Humain, Rat, Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Cellules d'insectes
- Type Proteine
- Recombinant
Dernières publications pour nos STAT3 Protéines
: "ApoC1 promotes the metastasis of clear cell renal cell carcinoma via activation of STAT3." dans: Oncogene, Vol. 39, Issue 39, pp. 6203-6217, (2021) (PubMed).
: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." dans: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).
: "KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer." dans: Molecular cancer, Vol. 13, pp. 176, (2014) (PubMed).
: "Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening." dans: Methods (San Diego, Calif.), Vol. 71, pp. 38-43, (2014) (PubMed).
: "AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer." dans: Theranostics, Vol. 8, Issue 3, pp. 676-692, (2018) (PubMed).
: "KIF5B-RET fusion kinase promotes cell growth by multilevel activation of STAT3 in lung cancer." dans: Molecular cancer, Vol. 13, pp. 176, (2014) (PubMed).
: "Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening." dans: Methods (San Diego, Calif.), Vol. 71, pp. 38-43, (2014) (PubMed).
Pseudonymes pour STAT3 Protéines
signal transducer and activator of transcription 3 (STAT3) Protéinessignal transduction and activation of transcription 3 (stat3) Protéines
signal transducer and activator of transcription 3 (stat3) Protéines
signal transducer and activator of transcription 3 (Stat3) Protéines
signal transducer and activator of transcription 3, gene 1 L homeolog (stat3.1.L) Protéines
signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) Protéines
1110034C02Rik Protéines
Aprf Protéines
APRF Protéines
aprf Protéines
AW109958 Protéines
HIES Protéines
hies Protéines
stat3 Protéines
wu:fc15d02 Protéines
wu:fl59g06 Protéines
Xstat3 Protéines
z-Stat3 Protéines
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