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STK39 Produits

(serine threonine Kinase 39 (STK39))
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008].

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Catégories STK39 en vedette

STK39 Anticorps

High quality antibodies with extensive validation data.

STK39 Kits ELISA

Reliable ELISA kits for a wide range of species.

STK39 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

STK39 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
  • (7)
N° du produit ABIN392497
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN570996
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN7180089
Quantité 100 μL
Fiche technique Fiche technique

STK39 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970113
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6959385
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381528
Quantité 96 tests
Fiche technique Fiche technique

STK39 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1321704
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5570584
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3120322
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits STK39

Mao, Ladd, Gad, Rastetter, Johnson, Marzbani, Childs, Lu, Dang, Broussard, Stanton, Hanash, Disis: "Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer." dans: Journal of translational medicine, Vol. 12, pp. 121, (2014) (PubMed).

Yang, Cai, Zhou, Chen, Chen, Chen, Wang, Fang, Zhou: "STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy." dans: PLoS ONE, Vol. 8, Issue 9, pp. e74614, (2013) (PubMed).

Arion, Lewis: "Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia." dans: Archives of general psychiatry, Vol. 68, Issue 1, pp. 21-31, (2011) (PubMed).

Wang, OConnell, McArdle, Wade, Dorff, Shah, Shi, Pan, Rampersaud, Shen, Kim, Subramanya, Steinle, Parsa, Ober, Welling, Chakravarti, Weder, Cooper, Mitchell, Shuldiner, Chang: "From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 1, pp. 226-31, (2009) (PubMed).

Smith, Smallwood, Altman, Liedtke: "PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells." dans: The Journal of biological chemistry, Vol. 283, Issue 32, pp. 22147-56, (2008) (PubMed).

Ramoz, Cai, Reichert, Silverman, Buxbaum: "An analysis of candidate autism loci on chromosome 2q24-q33: evidence for association to the STK39 gene." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 7, pp. 1152-8, (2008) (PubMed).

Yan, Nguyen, Dalmasso, Sitaraman, Merlin: "Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform." dans: Biochimica et biophysica acta, Vol. 1769, Issue 2, pp. 106-16, (2007) (PubMed).

Polek, Talpaz, Spivak-Kroizman: "TRAIL-induced cleavage and inactivation of SPAK sensitizes cells to apoptosis." dans: Biochemical and biophysical research communications, Vol. 349, Issue 3, pp. 1016-24, (2006) (PubMed).

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." dans: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).

Liedtke, Wang, Smallwood: "Role for protein phosphatase 2A in the regulation of Calu-3 epithelial Na+-K+-2Cl-, type 1 co-transport function." dans: The Journal of biological chemistry, Vol. 280, Issue 27, pp. 25491-8, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à STK39

serine/threonine kinase 39 (stk39), serine/threonine kinase 39 (STK39), serine/threonine kinase 39 L homeolog (stk39.L), serine threonine kinase 39 (Stk39), serine threonine kinase 39 (STK39), serine/threonine kinase 39 (Stk39), AW227544, AW556857, dcht, DCHT, MGC69537, pask, PASK, RF005, Rnl5, spak, SPAK, Spak

Protein level used designations for STK39

  • serine threonine kinase 39 (STE20/SPS1 homolog)
  • serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
  • serine threonine kinase 39
  • serine/threonine kinase 39
  • STE20/SPS1 homolog
  • STE20/SPS1-related proline-alanine-rich protein kinase
  • Ste20-like protein kinase
  • proline-alanine-rich STE20-related kinase
  • serine/threonine-protein kinase 39
  • small intestine SPAK-like kinase
  • ste-20-related kinase
  • PS/TK
  • PSTK1
  • Ste-20 related kinase
  • pancreatic serine/threonine-protein kinase
  • kidney-specific SPAK
  • serine/threonine kinase 39, STE20/SPS1 homolog
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