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TCF4 Produits

(Transcription Factor 4 (TCF4))
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Aug 2011].

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Catégories TCF4 en vedette

TCF4 Anticorps

High quality antibodies with extensive validation data.

TCF4 Kits ELISA

Reliable ELISA kits for a wide range of species.

TCF4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TCF4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
  • (5)
N° du produit ABIN520754
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (6)
N° du produit ABIN3021530
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (4)
N° du produit ABIN5542392
Quantité 0.1 mg
Fiche technique Fiche technique

TCF4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970768
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5661955
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1162244
Quantité 96 tests
Fiche technique Fiche technique

TCF4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1322369
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125438
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125439
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TCF4

Zheng, Lin, Wu, Mo, Lian, Wang, Hu, Gao, Peng, Xie: "Forkhead box (FOX) G1 promotes hepatocellular carcinoma epithelial-Mesenchymal transition by activating Wnt signal through forming T-cell factor-4/Beta-catenin/FOXG1 complex." dans: Journal of experimental & clinical cancer research : CR, Vol. 38, Issue 1, pp. 475, (2020) (PubMed).

Wosczyna, Konishi, Perez Carbajal, Wang, Walsh, Gan, Wagner, Rando: "Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle." dans: Cell reports, Vol. 27, Issue 7, pp. 2029-2035.e5, (2019) (PubMed).

Luo, Lim, Lee, Granter, Thomas, Vazquez, Widlund, Puigserver: "A PGC1α-mediated transcriptional axis suppresses melanoma metastasis." dans: Nature, Vol. 537, Issue 7620, pp. 422-426, (2016) (PubMed).

Forrest, Waite, Martin-Rendon, Blake: "Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation." dans: PLoS ONE, Vol. 8, Issue 8, pp. e73169, (2013) (PubMed).

Saegusa, Hashimura, Kuwata: "Sox4 functions as a positive regulator of β-catenin signaling through upregulation of TCF4 during morular differentiation of endometrial carcinomas." dans: Laboratory investigation; a journal of technical methods and pathology, Vol. 92, Issue 4, pp. 511-21, (2012) (PubMed).

Eichhoff, Weeraratna, Zipser, Denat, Widmer, Xu, Kriegl, Kirchner, Larue, Dummer, Hoek: "Differential LEF1 and TCF4 expression is involved in melanoma cell phenotype switching." dans: Pigment cell & melanoma research, Vol. 24, Issue 4, pp. 631-42, (2011) (PubMed).

Tanaka, Itoh, Nishiyama, Takezawa, Kurihara, Itoh, Kato: "Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis." dans: Blood, Vol. 115, Issue 20, pp. 4138-47, (2010) (PubMed).

Schenkel, Zloza, Li, Narasipura, Al-Harthi: "Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 4, pp. 2013-9, (2010) (PubMed).

Marusyk, Wheeler, Mathews, DeGregori: "p53 mediates senescence-like arrest induced by chronic replicational stress." dans: Molecular and cellular biology, Vol. 27, Issue 15, pp. 5336-51, (2007) (PubMed).

Tshori, Gilon, Beeri, Nechushtan, Kaluzhny, Pikarsky, Razin: "Transcription factor MITF regulates cardiac growth and hypertrophy." dans: The Journal of clinical investigation, Vol. 116, Issue 10, pp. 2673-81, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à TCF4

transcription factor 4 (TCF4), transcription factor 4 (Tcf4), transcription factor 4 (tcf4), transcription factor 4 S homeolog (tcf4.S), 5730422P05Rik, ASP-I2, bHLHb19, E2-2, e2-A, E2.2, ITF-2, ITF-2b, ITF2, ME2, MITF-2A, MITF-2B, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, Tcf-4, tcf-4, TCF7L2, TFE, XE2, Xtcf-4, Xtcf4

Protein level used designations for TCF4

  • SL3-3 enhancer factor 2
  • class B basic helix-loop-helix protein 19
  • immunoglobulin transcription factor 2
  • MITF-2
  • Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2)
  • class A helix-loop-helix transcription factor ME2
  • immunoglobulin transcription factor-2
  • ITF-2
  • R8f DNA-binding protein
  • RITF-2
  • SEF-2
  • TCF-4
  • thyroglobulin promoter transcription factor TFE
  • transcription factor 7-like 2 (T-cell specific, HMG-box)
  • transcriptional factor 4
  • tcf4l
  • helix-loop-helix transcription factor
  • LOW QUALITY PROTEIN: transcription factor 4
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