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TCF7L2 Produits

(Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Catégories

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010].

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Catégories TCF7L2 en vedette

TCF7L2 Anticorps

High quality antibodies with extensive validation data.

TCF7L2 Kits ELISA

Reliable ELISA kits for a wide range of species.

TCF7L2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TCF7L2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF (cc), IHC (p), FACS
Validations
  • (1)
  • (2)
  • (1)
N° du produit ABIN6945139
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (6)
N° du produit ABIN520778
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (4)
N° du produit ABIN563117
Quantité 100 μg
Fiche technique Fiche technique

TCF7L2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6970769
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960753
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6223776
Quantité 96 tests
Fiche technique Fiche technique

TCF7L2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (3)
N° du produit ABIN3095869
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1785451
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322377
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TCF7L2

Johnson, Drugan, Miller, Evans: "38" dans: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Zambanini, Nordin, Jonasson, Pagella, Cantù: "A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets." dans: Development (Cambridge, England), (2022) (PubMed).

Kwon, Leibovitch, Bansal, Pereira, Chung, Ariztia, Zelent, Farias, Waxman: "Targeted interference of SIN3A-TGIF1 function by SID decoy treatment inhibits Wnt signaling and invasion in triple negative breast cancer cells." dans: Oncotarget, Vol. 8, Issue 51, pp. 88421-88436, (2017) (PubMed).

Kang, Hou, Wang, Liu, Xiang, Xie, Zhang, Gan, Zheng, Miao: "Macrophage TCF-4 co-activates p65 to potentiate chronic inflammation and insulin resistance in mice." dans: Clinical science (London, England : 1979), Vol. 130, Issue 14, pp. 1257-68, (2016) (PubMed).

da Silva Xavier, Loder, McDonald, Tarasov, Carzaniga, Kronenberger, Barg, Rutter: "TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells." dans: Diabetes, Vol. 58, Issue 4, pp. 894-905, (2009) (PubMed).

Fancy, Baranzini, Zhao, Yuk, Irvine, Kaing, Sanai, Franklin, Rowitch: "Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS." dans: Genes & development, Vol. 23, Issue 13, pp. 1571-85, (2009) (PubMed).

Lukas, Mazna, Valenta, Doubravska, Pospichalova, Vojtechova, Fafilek, Ivanek, Plachy, Novak, Korinek: "Dazap2 modulates transcription driven by the Wnt effector TCF-4." dans: Nucleic acids research, Vol. 37, Issue 9, pp. 3007-20, (2009) (PubMed).

Shitashige, Satow, Honda, Ono, Hirohashi, Yamada: "Regulation of Wnt signaling by the nuclear pore complex." dans: Gastroenterology, Vol. 134, Issue 7, pp. 1961-71, 1971.e1-4, (2008) (PubMed).

Freedman, Sondermann, Friedland, Kortemme, Bar-Sagi, Marqusee, Kuriyan: "A Ras-induced conformational switch in the Ras activator Son of sevenless." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 45, pp. 16692-7, (2006) (PubMed).

Yang, Bashaw: "Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline." dans: Neuron, Vol. 52, Issue 4, pp. 595-607, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à TCF7L2

transcription factor 7 like 2 (TCF7L2), transcription factor 7-like 2 (LOC100545943), transcription factor 7 like 2, T cell specific, HMG box (Tcf7l2), transcription factor 7 like 2 (tcf7l2), transcription factor 7 like 2 L homeolog (tcf7l2.L), transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcription factor 7 like 2 (Tcf7l2), mTcf-4B, mTcf-4E, Tcf-4, TCF-4, Tcf4, tcf4, TCF4, TCF4B, TCF4E, tcf4e, TCFL2, XTCF-4

Protein level used designations for TCF7L2

  • transcription factor 7-like 2 (T-cell specific, HMG-box)
  • HMG box transcription factor 4
  • T-cell factor 4
  • T-cell-specific transcription factor 4
  • mTCF-4
  • transcription factor 7-like 2
  • transcription factor 7-like 2, T-cell specific, HMG-box
  • transcription factor tcf4
  • T-cell factor XTCF-4A
  • transcription factor Tcf4
  • T-cell factor-4 variant A
  • T-cell factor-4 variant B
  • T-cell factor-4 variant C
  • T-cell factor-4 variant D
  • T-cell factor-4 variant E
  • T-cell factor-4 variant F
  • T-cell factor-4 variant G
  • T-cell factor-4 variant H
  • T-cell factor-4 variant I
  • T-cell factor-4 variant J
  • T-cell factor-4 variant K
  • T-cell factor-4 variant L
  • T-cell factor-4 variant M
  • T-cell factor-4 variant X2
  • hTCF-4
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