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TdT Produits

(Deoxynucleotidyltransferase, terminal (DNTT))
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008].

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Catégories TdT en vedette

TdT Anticorps

High quality antibodies with extensive validation data.

TdT Kits ELISA

Reliable ELISA kits for a wide range of species.

TdT Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TdT recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (5)
N° du produit ABIN5542551
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application IHC
Validations
  • (3)
N° du produit ABIN7477595
Quantité 1 mL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (9)
  • (2)
N° du produit ABIN3043577
Quantité 100 μg
Fiche technique Fiche technique

TdT recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966320
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1130055
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1130053
Quantité 96 tests
Fiche technique Fiche technique

TdT recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3132708
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3073778
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5709413
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TdT

Mann, Newberg, Black, Jones, Amaya-Manzanares, Guzman-Rojas, Kodama, Ward, Rust, van der Weyden, Yew, Waters, Leung, Rogers, Rogers, McNoe, Selvanesan, Navin, Jenkins, Copeland, Mann: "Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq." dans: Nature biotechnology, Vol. 34, Issue 9, pp. 962-72, (2016) (PubMed).

Troshchynsky, Dzneladze, Chen, Sheng, Saridakis, Wu: "Functional analyses of polymorphic variants of human terminal deoxynucleotidyl transferase." dans: Genes and immunity, Vol. 16, Issue 6, pp. 388-98, (2015) (PubMed).

Zhang, Pei, Ru, Li, Liu: "Bone morphogenetic protein 7 upregulates the expression of nestin and glial fibrillary acidic protein in rats with cerebral ischemia-reperfusion injury." dans: Biomedical reports, Vol. 1, Issue 6, pp. 895-900, (2014) (PubMed).

Yang, Zhang, Ding, Huang, Chen, Wu, Wang, Wang, Chen: "Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer." dans: British journal of cancer, Vol. 110, Issue 5, pp. 1288-97, (2014) (PubMed).

Tochinai, Ando, Suzuki, Suzuki, Nagata, Hata, Uchida, Kobayashi, Kado, Kaneko: "Histopathological studies of microtubule disassembling agent-induced myocardial lesions in rats." dans: Experimental and toxicologic pathology : official journal of the Gesellschaft fu?r Toxikologische Pathologie, Vol. 65, Issue 6, pp. 737-43, (2013) (PubMed).

Zeng, Ke, Song, Yao, Hu, Zhang, Li, Yin: "Annexin A3 is associated with a poor prognosis in breast cancer and participates in the modulation of apoptosis in vitro by affecting the Bcl-2/Bax balance." dans: Experimental and molecular pathology, Vol. 95, Issue 1, pp. 23-31, (2013) (PubMed).

Xi, Wang, Ye, Luo, Ning: "Combined adenovirus-mediated artificial microRNAs targeting mfgl2, mFas, and mTNFR1 protect against fulminant hepatic failure in mice." dans: PLoS ONE, Vol. 8, Issue 11, pp. e82330, (2013) (PubMed).

Gong, Zheng, Wang, Chen, Pang, Hu, Cao: "Coexistence of hyperlipidemia and acute cerebral ischemia/reperfusion induces severe liver damage in a rat model." dans: World journal of gastroenterology, Vol. 18, Issue 35, pp. 4934-43, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à TdT

DNA nucleotidylexotransferase (DNTT), deoxynucleotidyltransferase, terminal (dntt), deoxynucleotidyltransferase, terminal (Dntt), DNA nucleotidylexotransferase L homeolog (dntt.L), DNA nucleotidylexotransferase (Dntt), terminal deoxynucleotidyl transferase (tdt), BB160593, dntt, dntt-A, TdT, TDT, Tdt

Protein level used designations for TdT

  • terminal deoxynucleotidyltransferase
  • DNA nucleotidylexotransferase
  • terminal deoxynucleotidyl transferase
  • TDT
  • terminal addition enzyme
  • terminal transferase
  • deoxynucleotidyltransferase, terminal
  • nucleosidetriphosphate:DNA deoxynucleotidylexotransferase
  • terminal deoxyribonucleotidyltransferase
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