TEK Produits
(TEK Tyrosine Kinase, Endothelial (TEK))
Catégories
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations\; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008].
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Catégories TEK en vedette
TEK Anticorps
High quality antibodies with extensive validation data.
TEK Kits ELISA
Reliable ELISA kits for a wide range of species.
TEK Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
TEK recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
N° du produit
ABIN1327048
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (4)
N° du produit
ABIN7249630
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
N° du produit
ABIN7193241
Quantité
0.1 mg
Fiche technique
Fiche technique
TEK recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
N° du produit
ABIN6730884
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6959878
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959877
Quantité
96 tests
Fiche technique
Fiche technique
TEK recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570126
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN6992355
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1322461
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits TEK
: "Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis." dans: eLife, Vol. 9, (2020) (PubMed).: "PADI4 stimulates esophageal squamous cell carcinoma tumor growth and up-regulates CA9 expression." dans: Molecular carcinogenesis, Vol. 58, Issue 1, pp. 66-75, (2019) (PubMed).
: "A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche." dans: Haematologica, (2019) (PubMed).
: "Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure." dans: Human reproduction (Oxford, England), Vol. 33, Issue 5, pp. 832-843, (2018) (PubMed).
: "MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. ..." dans: Gut, Vol. 67, Issue 2, pp. 333-347, (2018) (PubMed).
: "Tie2 protects the vasculature against thrombus formation in systemic inflammation." dans: The Journal of clinical investigation, Vol. 128, Issue 4, pp. 1471-1484, (2018) (PubMed).
: "Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF." dans: Oncotarget, Vol. 9, Issue 1, pp. 726-742, (2018) (PubMed).
: "Pulmonary pericytes regulate lung morphogenesis." dans: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).
: "Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs." dans: Molecular therapy. Nucleic acids, Vol. 10, pp. 349-360, (2018) (PubMed).
: "Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock." dans: Anesthesiology, Vol. 128, Issue 2, pp. 361-374, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à TEK
TEK receptor tyrosine kinase (TEK), angiopoietin-1 receptor (LOC100408334), TEK receptor tyrosine kinase (tek), TEK receptor tyrosine kinase (Tek), TEK tyrosine kinase, endothelial (tek), AA517024, Cd202b, CD202B, DKFZp469E064, Hyk, TEK, tie-2, TIE-2, Tie-2, Tie2, TIE2, tie2, VMCM, VMCM1Protein level used designations for TEK
- growth factor receptor Tie2/Tek
- TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)
- Angiopoietin-1 receptor
- TEK tyrosine kinase, endothelial
- angiopoietin-1 receptor-like
- STK1
- angiopoietin-1 receptor
- endothelial tyrosine kinase
- mTIE2
- p140 TEK
- tunica interna endothelial cell kinase
- tyrosine kinase with Ig and EGF homology domains-2
- tyrosine-protein kinase receptor TEK
- tyrosine-protein kinase receptor TIE-2
- hTIE2
- soluble TIE2 variant 1
- soluble TIE2 variant 2
- protein-tyrosine kinase Tie2
- endothelial-specific receptor tyrosine kinase
- tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2
- endothelium-specific receptor tyrosine kinase 2
- tyrosine-protein kinase receptor Tie-2
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