TGFB1 Protéines
(Transforming Growth Factor, beta 1 (TGFB1))
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].
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TGFB1
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
Dernières publications pour nos TGFB1 Protéines
: "Obesity reduces mammary epithelial cell TGFβ1 activity through macrophage-mediated extracellular matrix remodeling." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 6, pp. 8611-8624, (2020) (PubMed).
: "DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells." dans: Bioscience reports, Vol. 40, Issue 3, (2020) (PubMed).
: "Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells." dans: Molecular medicine reports, Vol. 21, Issue 1, pp. 249-257, (2020) (PubMed).
: "Exosomal miR-532-5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5." dans: Experimental cell research, Vol. 393, Issue 2, pp. 112109, (2020) (PubMed).
: "Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells." dans: Molecular medicine reports, Vol. 19, Issue 2, pp. 1159-1167, (2019) (PubMed).
: "Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction." dans: Molecular medicine reports, Vol. 19, Issue 4, pp. 3168-3178, (2019) (PubMed).
: "Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: Reduction of PPARα." dans: Biochimie, Vol. 160, pp. 172-182, (2019) (PubMed).
: "Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation." dans: Life sciences, Vol. 232, pp. 116609, (2019) (PubMed).
: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." dans: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).
: "Active Traction Force Response to Long-Term Cyclic Stretch Is Dependent on Cell Pre-stress." dans: Biophysical journal, Vol. 110, Issue 8, pp. 1845-1857, (2017) (PubMed).
: "DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells." dans: Bioscience reports, Vol. 40, Issue 3, (2020) (PubMed).
: "Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells." dans: Molecular medicine reports, Vol. 21, Issue 1, pp. 249-257, (2020) (PubMed).
: "Exosomal miR-532-5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5." dans: Experimental cell research, Vol. 393, Issue 2, pp. 112109, (2020) (PubMed).
: "Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells." dans: Molecular medicine reports, Vol. 19, Issue 2, pp. 1159-1167, (2019) (PubMed).
: "Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction." dans: Molecular medicine reports, Vol. 19, Issue 4, pp. 3168-3178, (2019) (PubMed).
: "Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: Reduction of PPARα." dans: Biochimie, Vol. 160, pp. 172-182, (2019) (PubMed).
: "Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation." dans: Life sciences, Vol. 232, pp. 116609, (2019) (PubMed).
: "ROCK Inhibitor Y27632 Induced Morphological Shift and Enhanced Neurite Outgrowth-Promoting Property of Olfactory Ensheathing Cells via YAP-Dependent Up-Regulation of L1-CAM." dans: Frontiers in cellular neuroscience, Vol. 12, pp. 489, (2018) (PubMed).
: "Active Traction Force Response to Long-Term Cyclic Stretch Is Dependent on Cell Pre-stress." dans: Biophysical journal, Vol. 110, Issue 8, pp. 1845-1857, (2017) (PubMed).
Pseudonymes pour TGFB1 Protéines
transforming growth factor beta 1 (TGFB1) Protéinestransforming growth factor beta-1 (TGFB1) Protéines
transforming growth factor beta 1 (Tgfb1) Protéines
transforming growth factor beta 1 L homeolog (tgfb1.L) Protéines
transforming growth factor, beta 1 (Tgfb1) Protéines
transforming growth factor, beta 1a (tgfb1a) Protéines
transforming growth factor beta induced L homeolog (tgfbi.L) Protéines
ai39657 Protéines
betaig-h3 Protéines
bigh3 Protéines
cdb1 Protéines
cdg2 Protéines
cdgg1 Protéines
CED Protéines
ced Protéines
csd Protéines
csd1 Protéines
csd2 Protéines
csd3 Protéines
DPD1 Protéines
dpd1 Protéines
ebmd Protéines
LAP Protéines
lap Protéines
lcd1 Protéines
TGF-beta Protéines
tgf-beta Protéines
TGF-BETA-1 Protéines
TGF-beta1 Protéines
TGF-beta5 Protéines
TGFB Protéines
tgfb Protéines
Tgfb Protéines
Tgfb-1 Protéines
tgfb1 Protéines
TGFB1 Protéines
TGFB4 Protéines
tgfb5 Protéines
TGFbeta Protéines
tgfbeta Protéines
TGFbeta1 Protéines
wu:fb13a07 Protéines
xx:ai39657 Protéines
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