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THEMIS Produits

(Thymocyte Selection Associated (THEMIS))
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Catégories THEMIS en vedette

THEMIS Anticorps

High quality antibodies with extensive validation data.

THEMIS Kits ELISA

Reliable ELISA kits for a wide range of species.

THEMIS Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

THEMIS recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7166179
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (3)
N° du produit ABIN1714633
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN655135
Quantité 400 μL
Fiche technique Fiche technique

THEMIS recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959950
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959951
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6233838
Quantité 96 tests
Fiche technique Fiche technique

THEMIS recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN2752947
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3073988
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3136150
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits THEMIS

Paster, Bruger, Katsch, Grégoire, Roncagalli, Fu, Gascoigne, Nika, Cohnen, Feller, Simister, Molder, Cordoba, Dushek, Malissen, Acuto: "A THEMIS:SHP1 complex promotes T-cell survival." dans: The EMBO journal, Vol. 34, Issue 3, pp. 393-409, (2015) (PubMed).

Fu, Vallée, Rybakin, McGuire, Ampudia, Brockmeyer, Salek, Fallen, Hoerter, Munshi, Huang, Hu, Fox, Sauer, Acuto, Gascoigne: "Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling." dans: Nature immunology, Vol. 10, Issue 8, pp. 848-56, (2009) (PubMed).

Johnson, Aravind, Shulzhenko, Morgun, Choi, Crockford, Lambe, Domaschenz, Kucharska, Zheng, Vinuesa, Lenardo, Goodnow, Cornall, Schwartz: "Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection." dans: Nature immunology, Vol. 10, Issue 8, pp. 831-9, (2009) (PubMed).

Lesourne, Uehara, Lee, Song, Li, Pinkhasov, Zhang, Weng, Wildt, Wang, Bosselut, Love: "Themis, a T cell-specific protein important for late thymocyte development." dans: Nature immunology, Vol. 10, Issue 8, pp. 840-7, (2009) (PubMed).

Patrick, Oda, Hayakawa, Sato, Eshima, Kirikae, Iemura, Shirai, Abe, Natsume, Sasazuki, Suzuki: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à THEMIS

thymocyte selection associated (THEMIS), thymocyte selection associated (Themis), thymocyte selection associated (themis), A430108D01, bA325O24.3, bA325O24.4, BB160712, C6orf190, C6orf207, C9H6ORF190, E430004N04Rik, GASP, Gasp, im:7138580, SPOT, thylex, TSEPA, Tsepa, tsepa

Protein level used designations for THEMIS

  • thymocyte selection associated
  • thymocyte selection pathway associated
  • GRB2-associated protein
  • protein THEMIS
  • signaling phosphoprotein specific for T cells
  • thymocyte expressed molecule involved in selection
  • thymocyte-expressed molecule involved in selection
  • grb2-associating protein
  • protein thylex
  • thymus lymphocyte exclusively expressed
  • Thymocyte-expressed molecule involved in selection
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