THC Anticorps
(Tetrahydrocannabinol (THC))
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008].
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Catégories THC en vedette
THC Anticorps
High quality antibodies with extensive validation data.
THC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Various Species
Application
ELISA, LF
Validations
N° du produit
ABIN7384961
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Chemical
Application
ELISA
Validations
N° du produit
ABIN3027491
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Chemical
Application
ELISA, LF
Validations
N° du produit
ABIN3027493
Quantité
1 mg
Fiche technique
Fiche technique
Synonymes et noms alternatifs relatifs à THC
Wiskott-Aldrich syndrome (WAS), IMD2, SCNX, THC, THC1, WASPProtein level used designations for THC
- eczema-thrombocytopenia
- thrombocytopenia 1 (X-linked)
- wiskott-Aldrich syndrome protein
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