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TLK1 Produits

(Tousled-Like Kinase 1 (TLK1))

Catégories

The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

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Catégories TLK1 en vedette

TLK1 Anticorps

High quality antibodies with extensive validation data.

TLK1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TLK1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN392685
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IP, ICC
Validations
  • (1)
  • (3)
N° du produit ABIN2855507
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN564253
Quantité 100 μg
Fiche technique Fiche technique

TLK1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5570635
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1322843
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7317054
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits TLK1

Timiri Shanmugam, Nair, DeBenedetti, Caldito, Abreo, Sunavala-Dossabhoy: "DNA damage response and repair data with pharmacological modulators of Tousled." dans: Data in brief, Vol. 7, pp. 1073-7, (2016) (PubMed).

Awate, De Benedetti: "TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint." dans: BMC molecular biology, Vol. 17, pp. 3, (2016) (PubMed).

Takayama, Kokuryo, Yokoyama, Ito, Nagino, Hamaguchi, Senga: "Silencing of Tousled-like kinase 1 sensitizes cholangiocarcinoma cells to cisplatin-induced apoptosis." dans: Cancer letters, Vol. 296, Issue 1, pp. 27-34, (2010) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Krause, Jonnalagadda, Gatei, Sillje, Zhou, Nigg, Khanna: "Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1." dans: Oncogene, Vol. 22, Issue 38, pp. 5927-37, (2003) (PubMed).

Cabaniols, Ravichandran, Roche: "Phosphorylation of SNAP-23 by the novel kinase SNAK regulates t-SNARE complex assembly." dans: Molecular biology of the cell, Vol. 10, Issue 12, pp. 4033-41, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à TLK1

tousled like kinase 1 (TLK1), tousled-like kinase 1 (Tlk1), tousled-like kinase 1b (tlk1b), tousled like kinase 1 like (TLK1L), tousled-like kinase 1 (TLK1), serine/threonine-protein kinase TOUSLED (LOC542181), tousled-like kinase 1a (tlk1a), tousled like kinase 1 (tlk1), Serine/threonine-protein kinase tousled-like 1 (tlk-1), tousled like kinase 1 (Tlk1), 4930545J15Rik, DKFZp459L163, fb76h12, fe11e12, PKU-beta, si:dkey-88m1.1, si:dkey-251e16.4, tlk1, TLK1, wu:fb76h12, wu:fe11e12

Protein level used designations for TLK1

  • SNARE protein kinase SNAK
  • serine threonine protein kinase
  • serine/threonine-protein kinase tousled-like 1
  • pKU-beta protein kinase
  • serine/threonine-protein kinase tousled-like 1-B
  • tousled-like kinase 1
  • tousled-like kinase 1-B
  • LOW QUALITY PROTEIN: serine/threonine-protein kinase tousled-like 1
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