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TNKS Protéines

(Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination. Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length. May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles.

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TNKS Protein (AA 1-1320) (His tag)

custom-made TNKS Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Tnks Protein, UniprotID Q6PFX9

3 images

N° du produit ABIN7564126

Détails

TNKS Protein (AA 1-1327) (His tag)

custom-made TNKS Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant TNKS Protein, UniprotID O95271

3 images

N° du produit ABIN7555777

Détails

TNKS Protein (AA 1105-1327) (His tag)

TNKS Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

N° du produit ABIN7397048

Détails

TNKS Protein (AA 1-1320) (Strep Tag)

custom-made TNKS Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3135804

Détails

TNKS Protein (AA 1-1327) (Strep Tag)

custom-made TNKS Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). SDS, WB, ELISA

N° du produit ABIN3095915