TNFSF9 Protéines
(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| TNFSF9 Protein (AA 71-254, Trimer) (Fc Tag,DYKDDDDK Tag) | Humain | HEK-293 Cells |
|
397,11 €
Voir le prix
|
|
| TNFSF9 Protein (AA 71-254, Trimer) (Fc Tag,Biotin,DYKDDDDK Tag) | Humain | HEK-293 Cells |
|
628,47 €
Voir le prix
|
|
| TNFSF9 Protein (AA 71-254, Trimer) (His-DYKDDDDK Tag) | Humain | HEK-293 Cells |
|
397,11 €
Voir le prix
|
|
| TNFSF9 Protein (AA 68-251) (hFc Tag) | Cynomolgus | HEK-293 Cells |
|
397,11 €
Voir le prix
|
|
| TNFSF9 Protein (AA 99-330) (His tag,mFc Tag) | Humain | HEK-293 Cells |
|
915,38 €
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|
|
| TNFSF9 Protein (AA 50-254) (His-DYKDDDDK-Strep II Tag) | Humain | HEK-293T Cells |
|
952,00 €
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|
|
| TNFSF9 Protein (AA 99-330) (Fc Tag) | Souris | HEK-293 Cells |
|
988,62 €
Voir le prix
|
|
| TNFSF9 Protein (AA 71-254) (His-IF2DI Tag) | Humain | Escherichia coli (E. coli) |
|
476,92 €
Voir le prix
|
|
| TNFSF9 Protein (AA 104-309) (His tag) | Souris | HEK-293 Cells |
|
287,60 €
Voir le prix
|
|
| TNFSF9 Protein (His tag) | Humain | Escherichia coli (E. coli) |
|
2.369,23 €
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|
|
| TNFSF9 Protein (AA 71-254) (DYKDDDDK-His Tag) | Humain | Human Cells |
|
193,09 €
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|
|
| TNFSF9 Protein (AA 1-254) (Strep Tag) | Humain | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
Voir le prix
|
|
| TNFSF9 Protein (AA 1-309) (Strep Tag) | Souris | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
Voir le prix
|
|
| TNFSF9 Protein (AA 50-254, Extracellular Domain, N-Term, Soluble) (DYKDDDDK Tag) | Humain | HEK-293 Cells |
|
541,38 €
Voir le prix
|
|
| TNFSF9 Protein (AA 104-309, Extracellular Domain, N-Term, Soluble) (DYKDDDDK Tag) | Souris | HEK-293 Cells |
|
516,62 €
Voir le prix
|
|
| TNFSF9 Protein (AA 104-309) (hFc Tag) | Souris | HEK-293 Cells |
|
397,11 €
Voir le prix
|
|
| TNFSF9 Protein (AA 104-309) (hFc Tag) | Souris | HEK-293 Cells |
|
431,66 €
Voir le prix
|
|
| TNFSF9 Protein (AA 4-1, AA 104-309) (His tag) | Souris | Mammalian Cells |
|
486,15 €
Voir le prix
|
|
| TNFSF9 Protein (AA 71-254) (His tag) | Humain | Escherichia coli (E. coli) |
|
468,07 €
Voir le prix
|
|
| TNFSF9 Protein (His tag) | Souris | Escherichia coli (E. coli) |
|
278,46 €
Voir le prix
|
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- ELISA (ELISA: Image de validation disponible)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Image de validation disponible)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- ELISA (ELISA: Image de validation disponible)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Image de validation disponible)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC
- Activité biologique
- Active
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Image de validation disponible)
- ELISA (ELISA: Image de validation disponible)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- ELISA (ELISA: Image de validation disponible)
- SEC-HPLC (Size-exclusion chromatography-High Pressure Liquid Chromatography: Image de validation disponible)
- Origine
- Cynomolgus
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- FACS (Flow Cytometry: Image de validation disponible)
- AM (Affinity Measurement: Application indiquée)
- ADA (Antibody Drug Assay: Application indiquée)
- IA (Immunoassay: Application indiquée)
- ScA (Screening Assay: Application indiquée)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- WB (Western Blotting: Image de validation disponible)
- ELISA (ELISA: Application indiquée)
- PI (Protein Interaction: Application indiquée)
- Origine
- Humain
- Hôte
- HEK-293T Cells
- Type Proteine
- Recombinant
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- AM (Affinity Measurement: Application indiquée)
- ADA (Antibody Drug Assay: Application indiquée)
- IA (Immunoassay: Application indiquée)
- ScA (Screening Assay: Application indiquée)
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- WB (Western Blotting: Image de validation disponible)
- ELISA (ELISA: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: Image de validation disponible)
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- WB (Western Blotting: Application indiquée)
- Classe de qualité
- GMP Grade
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >95 %
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- Human Cells
- Type Proteine
- Recombinant
Protein
- WB (Western Blotting: Application indiquée)
- SDS (SDS-PAGE: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Humain
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: Application indiquée)
- SDS (SDS-PAGE: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Souris
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- >90 % (SDS-PAGE)
Protein
- SDS (SDS-PAGE: Application indiquée)
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- >95 % (SDS-PAGE)
Protein
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Souris
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 90 % as determined by SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >95 %
- Activité biologique
- Active
Dernières publications pour nos TNFSF9 Protéines
: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." dans: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).
: "Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity." dans: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41472-81, (2005) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "[Binding between alpha 1A-adrenergic receptor and segment of bone morphogenetic protein-1 in human embryonic cell 293]." dans: Sheng li xue bao : [Acta physiologica Sinica], Vol. 55, Issue 6, pp. 692-8, (2003) (PubMed).
: "Molecular and biological characterization of human 4-1BB and its ligand." dans: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, (1994) (PubMed).
: "Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity." dans: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41472-81, (2005) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." dans: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "[Binding between alpha 1A-adrenergic receptor and segment of bone morphogenetic protein-1 in human embryonic cell 293]." dans: Sheng li xue bao : [Acta physiologica Sinica], Vol. 55, Issue 6, pp. 692-8, (2003) (PubMed).
: "Molecular and biological characterization of human 4-1BB and its ligand." dans: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, (1994) (PubMed).
Pseudonymes pour TNFSF9 Protéines
TNF superfamily member 9 (Tnfsf9) ProtéinesTNF superfamily member 9 (LOC476729) Protéines
TNF superfamily member 9 (TNFSF9) Protéines
tumor necrosis factor (ligand) superfamily, member 9 (Tnfsf9) Protéines
4-1BB-L Protéines
4-1BBL Protéines
AI848817 Protéines
Cd137l Protéines
CD137L Protéines
Ly63l Protéines
TNFSF9 Protéines
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