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TPSAB1 Produits

(Tryptase alpha/beta 1 (TPSAB1))
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells\; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008].

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Catégories TPSAB1 en vedette

TPSAB1 Anticorps

High quality antibodies with extensive validation data.

TPSAB1 Kits ELISA

Reliable ELISA kits for a wide range of species.

TPSAB1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

TPSAB1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7433105
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7426172
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7428305
Quantité 100 μL
Fiche technique Fiche technique

TPSAB1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (6)
N° du produit ABIN6574250
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960219
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6960221
Quantité 96 tests
Fiche technique Fiche technique

TPSAB1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Cynomolgus
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7275682
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1323462
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3075013
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits TPSAB1

Rathore, Mantri, Aman, Syenina, Ooi, Jagaraj, Goh, Tissera, Wilder-Smith, Ng, Gubler, St John: "Dengue virus-elicited tryptase induces endothelial permeability and shock." dans: The Journal of clinical investigation, Vol. 129, Issue 10, pp. 4180-4193, (2020) (PubMed).

Galiazzo, Giancola, Stanzani, Fracassi, Bernardini, Forni, Pietra, Chiocchetti: "Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract." dans: Histochemistry and cell biology, Vol. 150, Issue 2, pp. 187-205, (2018) (PubMed).

Wang, Chen, Xie, Lin, Wang, Yao, Zheng, Xu, Chen, He, Zhang: "Altered Expression of IFN-λ2 in Allergic Airway Disorders and Identification of Its Cell Origins." dans: Mediators of inflammation, Vol. 2016, pp. 5759496, (2016) (PubMed).

Moreno, Puig, Serrano, Moreno-Navarrete, Ortega, Ricart, Fernandez-Real: "Circulating tryptase as a marker for subclinical atherosclerosis in obese subjects." dans: PLoS ONE, Vol. 9, Issue 5, pp. e97014, (2015) (PubMed).

Berdún, Bombuy, Estrada, Mans, Rychter, Clavé, Vergara: "Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery." dans: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, Vol. 27, Issue 6, pp. 764-74, (2015) (PubMed).

Zhu, Pan, Wang, Liu, Chen, Xu, Liao, Hu: "Tryptase and protease-activated receptor-2 stimulate scratching behavior in a murine model of ovalbumin-induced atopic-like dermatitis." dans: International immunopharmacology, Vol. 28, Issue 1, pp. 507-12, (2015) (PubMed).

Lewicki, Siebert, Marek-Trzonkowska, Masiewicz, Kolinski, Reiwer-Gostomska, Targonski, Trzonkowski: "Elevated Serum Tryptase and Endothelin in Patients with ST Segment Elevation Myocardial Infarction: Preliminary Report." dans: Mediators of inflammation, Vol. 2015, pp. 395173, (2015) (PubMed).

Yan, Yao, Bao, Shi, Yu, Yin, Liu: "Effect of Auricular Acupressure on Uremic Pruritus in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 593196, (2015) (PubMed).

Naoi, Hayashi, Inoue, Tanikawa, Igarashi, Nagasaka, Kage, Takikawa, Sugiyama, Inui, Nagai, Kusuhara: "Improved liver function and relieved pruritus after 4-phenylbutyrate therapy in a patient with progressive familial intrahepatic cholestasis type 2." dans: The Journal of pediatrics, Vol. 164, Issue 5, pp. 1219-1227.e3, (2014) (PubMed).

El Gamal, AlSaid, Raish, Al-Sohaibani, Al-Massarani, Ahmad, Hefnawy, Al-Yahya, Basoudan, Rafatullah: "Beetroot (Beta vulgaris L.) extract ameliorates gentamicin-induced nephrotoxicity associated oxidative stress, inflammation, and apoptosis in rodent model." dans: Mediators of inflammation, Vol. 2014, pp. 983952, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à TPSAB1

tryptase alpha/beta 1 (TPSAB1), tryptase (MCT7), tryptase alpha/beta 1 (tpsab1), tryptase beta 2 (gene/pseudogene) (TPSB2), tryptase alpha/beta 1 (Tpsab1), tryptase beta 2 (Tpsb2), AV011504, Mcp-6, Mcp-7, Mcp6, Mcp7, Mcpt6, Mcpt7, MMCP-6, MMCP-7, PMCT7, rMCP-7, TPS1, TPS2, tpsab1, TPSB1, tryptaseB, tryptaseC

Protein level used designations for TPSAB1

  • mast cell alpha II tryptase
  • mast cell beta I tryptase
  • tryptase I
  • tryptase alpha II
  • tryptase alpha-1
  • tryptase alpha/beta-1
  • tryptase beta 1
  • tryptase beta I
  • tryptase beta-1
  • tryptase-1
  • tryptase-I
  • tryptase-III
  • tryptase alpha/beta 1
  • mast cell tryptase beta II
  • mast cell tryptase beta III
  • tryptase beta-2
  • mast cell protease 7
  • mast cell-restricted serine protease 7
  • tryptase
  • MMCP-7
  • tryptase, skin
  • mast cell protease 6
  • tryptase-2
  • rMCP-6
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