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UBE2L6 Produits

(Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Catégories

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011].

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Catégories UBE2L6 en vedette

UBE2L6 Anticorps

High quality antibodies with extensive validation data.

UBE2L6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

UBE2L6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
N° du produit ABIN563994
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN1683197
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
  • (2)
N° du produit ABIN1882146
Quantité 400 μL
Fiche technique Fiche technique

UBE2L6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6222131
Quantité 96 tests
Fiche technique Fiche technique

UBE2L6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125622
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324386
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN667729
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits UBE2L6

Zhao, Sridharan, Chen, Baker, Wang, Krug: "Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins." dans: Nature communications, Vol. 7, pp. 12754, (2018) (PubMed).

Takenokuchi, Miyamoto, Saigo, Taniguchi: "Bortezomib Causes ER Stress-related Death of Acute Promyelocytic Leukemia Cells Through Excessive Accumulation of PML-RARA." dans: Anticancer research, Vol. 35, Issue 6, pp. 3307-16, (2015) (PubMed).

Pietschmann, Buchwald, Müller, Knauer, Kögl, Heinzel, Krämer: "Differential regulation of PML-RAR? stability by the ubiquitin ligases SIAH1/SIAH2 and TRIAD1." dans: The international journal of biochemistry & cell biology, Vol. 44, Issue 1, pp. 132-8, (2011) (PubMed).

Hsiang, Zhao, Krug: "Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells." dans: Journal of virology, Vol. 83, Issue 12, pp. 5971-7, (2009) (PubMed).

Zhang, Adyshev, Singleton, Li, Cepeda, Huang, Zou, Verin, Tu, Garcia, Ye: "Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury." dans: FEBS letters, Vol. 582, Issue 13, pp. 1802-8, (2008) (PubMed).

Makki, Heinzel, Englert: "TSA downregulates Wilms tumor gene 1 (Wt1) expression at multiple levels." dans: Nucleic acids research, Vol. 36, Issue 12, pp. 4067-78, (2008) (PubMed).

Krämer, Müller, Buchwald, Reichardt, Heinzel: "Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 5, pp. 1369-79, (2008) (PubMed).

Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." dans: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).

Ardley, Rose, Tan, Leek, Markham, Robinson: "Genomic organization of the human ubiquitin-conjugating enzyme gene, UBE2L6 on chromosome 11q12." dans: Cytogenetics and cell genetics, Vol. 89, Issue 1-2, pp. 137-40, (2000) (PubMed).

Kumar, Kao, Howley: "Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity." dans: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13548-54, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à UBE2L6

ubiquitin conjugating enzyme E2 L6 (UBE2L6), ubiquitin-conjugating enzyme E2L 6 (Ube2l6), 2810489I21Rik, RIG-B, Ubce8, UBCH8, Ubcm8, UbcM8, UBE2L6

Protein level used designations for UBE2L6

  • ubiquitin-conjugating enzyme E2L 6
  • ubiquitin/ISG15-conjugating enzyme E2 L6
  • retinoic acid induced gene B protein
  • retinoic acid-induced gene B protein
  • ubiquitin carrier protein L6
  • ubiquitin-protein ligase L6
  • E2 ubiquitin conjugating enzyme
  • ubiquitin-conjugating enzyme 8
  • ubcM8
  • Ubiquitin carrier protein L6
  • Ubiquitin-protein ligase L6
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