UBE2D1 Produits
(Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
Catégories
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Catégories UBE2D1 en vedette
UBE2D1 Anticorps
High quality antibodies with extensive validation data.
UBE2D1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
UBE2D1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN521211
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (4)
N° du produit
ABIN7259985
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7174434
Quantité
100 μg
Fiche technique
Fiche technique
UBE2D1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6951479
Quantité
96 tests
Fiche technique
Fiche technique
UBE2D1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125608
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324340
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324342
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits UBE2D1
: "UBE2L3 polymorphism amplifies NF-?B activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases." dans: American journal of human genetics, Vol. 96, Issue 2, pp. 221-34, (2015) (PubMed).: "The stability of herpes simplex virus 1 ICP0 early after infection is defined by the RING finger and the UL13 protein kinase." dans: Journal of virology, Vol. 88, Issue 10, pp. 5437-43, (2014) (PubMed).
: "Exposure to cigarette smoke induces overexpression of von Hippel-Lindau tumor suppressor in mouse skeletal muscle." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 303, Issue 6, pp. L519-27, (2012) (PubMed).
: "A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter." dans: Nature cell biology, Vol. 5, Issue 8, pp. 754-61, (2003) (PubMed).
: "UbcH5A, a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, a stimulator of iron transport, and is up-regulated in hereditary hemochromatosis." dans: Blood, Vol. 101, Issue 8, pp. 3288-93, (2003) (PubMed).
: "Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 19, pp. 10430-5, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à UBE2D1
ubiquitin conjugating enzyme E2 D1 (UBE2D1), ubiquitin-conjugating enzyme E2D 1 (Ube2d1), ubiquitin-conjugating enzyme E2D 1b (ube2d1b), ubiquitin conjugating enzyme E2 D1 S homeolog (ube2d1.S), ubiquitin conjugating enzyme E2 D1 (ube2d1), ubiquitin conjugating enzyme E2 D1 (Ube2d1), E2(17)KB1, e2(17)kb1, SFT, sft, UBC4/5, ubc4/5, UBCH5, ubch5, UBCH5A, ubch5a, ube2d1, wu:fc16h06, zgc:73096Protein level used designations for UBE2D1
- UBC4/5 homolog
- stimulator of Fe transport
- ubiquitin carrier protein D1
- ubiquitin-conjugating enzyme E2 D1
- ubiquitin-conjugating enzyme E2(17)KB 1
- ubiquitin-conjugating enzyme E2-17 kDa 1
- ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
- ubiquitin-protein ligase D1
- E2(17)KB 1
- ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog
- ubiquitin-conjugating enzyme E2D 1
- ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog)
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