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Ubiquilin 1 Produits

(Ubiquilin 1 (UBQLN1))
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories Ubiquilin 1 en vedette

Ubiquilin 1 Anticorps

High quality antibodies with extensive validation data.

Ubiquilin 1 Kits ELISA

Reliable ELISA kits for a wide range of species.

Ubiquilin 1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Ubiquilin 1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p), IF
Validations
  • (3)
  • (3)
N° du produit ABIN388966
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Rabbit, Sheep
Application WB, IHC, IHC (p)
Validations
  • (4)
N° du produit ABIN6741620
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (5)
N° du produit ABIN3029415
Quantité 0.4 mL
Fiche technique Fiche technique

Ubiquilin 1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971031
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6208313
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1164827
Quantité 96 tests
Fiche technique Fiche technique

Ubiquilin 1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324458
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN3096220
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2734885
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Ubiquilin 1

Chen, Wang, Jiang, Zheng, Justice, Wang, Ran, Li, Huo, Zhang, Li, Lu, Wang, Zheng, Long, Yang: "APP modulates KCC2 expression and function in hippocampal GABAergic inhibition." dans: eLife, Vol. 6, (2018) (PubMed).

Sun, Liu, Yuan, Guo, Xie, Du, Lin, Xu, Liu, Wang, Yuan, Chen: "MiR-200c inhibits autophagy and enhances radiosensitivity in breast cancer cells by targeting UBQLN1." dans: International journal of cancer. Journal international du cancer, Vol. 136, Issue 5, pp. 1003-12, (2014) (PubMed).

Bieniek, Murray, Rutherford, Castanedes-Casey, DeJesus-Hernandez, Liesinger, Baker, Boylan, Rademakers, Dickson: "Tau pathology in frontotemporal lobar degeneration with C9ORF72 hexanucleotide repeat expansion." dans: Acta neuropathologica, Vol. 125, Issue 2, pp. 289-302, (2013) (PubMed).

Bao, Zhang, Zheng, Xu, Yan: "UBQLN1 interacts with SPEM1 and participates in spermiogenesis." dans: Molecular and cellular endocrinology, Vol. 327, Issue 1-2, pp. 89-97, (2010) (PubMed).

Sick, Boukhari, Deramaudt, Rondé, Bucher, André, Gies, Takeda: "Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway." dans: Glia, Vol. 59, Issue 2, pp. 308-19, (2010) (PubMed).

Massey, Mah, Ford, Miller, Liang, Doong, Monteiro: "Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins." dans: Journal of Alzheimer's disease : JAD, Vol. 6, Issue 1, pp. 79-92, (2004) (PubMed).

Gao, Tu, Shi, Lee, Asanaka, Hwang, Lai: "Interaction with a ubiquitin-like protein enhances the ubiquitination and degradation of hepatitis C virus RNA-dependent RNA polymerase." dans: Journal of virology, Vol. 77, Issue 7, pp. 4149-59, (2003) (PubMed).

Kleijnen, Shih, Zhou, Kumar, Soccio, Kedersha, Gill, Howley: "The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome." dans: Molecular cell, Vol. 6, Issue 2, pp. 409-19, (2000) (PubMed).

Mah, Perry, Smith, Monteiro: "Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation." dans: The Journal of cell biology, Vol. 151, Issue 4, pp. 847-62, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à Ubiquilin 1

ubiquilin 1 (UBQLN1), ubiquilin 1 (Ubqln1), 1110046H03Rik, 1810030E05Rik, AU019746, C77538, D13Ertd372e, DA41, Da41, DSK2, Dsk2, PLIC-1, Plic-1, Plic1, UBQLN1, UBQN, XDRP1, Xdrp1

Protein level used designations for Ubiquilin 1

  • ubiquilin-1
  • ubiquilin 1
  • ubiquilin-1-like
  • hPLIC-1
  • protein linking IAP with cytoskeleton 1
  • PLIC-1
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