Ubiquilin 2 Produits
(Ubiquilin 2 (UBQLN2))
Catégories
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases\; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009].
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Catégories Ubiquilin 2 en vedette
Ubiquilin 2 Anticorps
High quality antibodies with extensive validation data.
Ubiquilin 2 Kits ELISA
Reliable ELISA kits for a wide range of species.
Ubiquilin 2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Ubiquilin 2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (11)
- (7)
N° du produit
ABIN565449
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN6149859
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (3)
N° du produit
ABIN542720
Quantité
400 μL
Fiche technique
Fiche technique
Ubiquilin 2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971032
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960336
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN5591997
Quantité
96 tests
Fiche technique
Fiche technique
Ubiquilin 2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324460
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324462
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125571
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Ubiquilin 2
: "Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 49, pp. E11485-E11494, (2019) (PubMed).: "Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 44, pp. E10495-E10504, (2018) (PubMed).
: "Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control." dans: Cell, Vol. 171, Issue 4, pp. 918-933.e20, (2017) (PubMed).
: "UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome." dans: Cell, Vol. 166, Issue 4, pp. 935-49, (2016) (PubMed).
: "Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 47, pp. E7580-E7589, (2016) (PubMed).
: "Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." dans: Journal of neuropathology and experimental neurology, (2016) (PubMed).
: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." dans: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).
: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." dans: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).
: "Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice." dans: Molecular neurodegeneration, Vol. 10, pp. 25, (2015) (PubMed).
: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." dans: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à Ubiquilin 2
ubiquilin 2 (UBQLN2), ubiquilin 2 (Ubqln2), ALS15, CHAP1, Chap1, DSK2, Dsk2, HRIHFB2157, N4BP4, Plic-2, PLIC2, Plic2, RGD1563566, UBQLN2Protein level used designations for Ubiquilin 2
- Nedd4 binding protein 4
- protein linking IAP with cytoskeleton 2
- ubiquilin-2
- ubiquitin-like product Chap1/Dsk2
- Ubiquitin-related protein
- ubiquilin 2
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- UBE2Z
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- UBE2V2
- UBE2V1
- UBE2U
- Ube2t
- UBE2S.2
- UBE2R2
- UBE2QL1
- Ubiquilin 3
- Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 3
- Ubiquinol-Cytochrome C Reductase Complex Chaperone
- Ubiquinol-Cytochrome C Reductase Core Protein II
- Ubiquitin
- Ubiquitin +1
- Ubiquitin 11
- Ubiquitin Associated Protein 1
- Ubiquitin B
- Ubiquitin Specific Peptidase 12
- Ubiquitin-Conjugating Enzyme E2D 3
- Ubiquitin-Conjugating Enzyme E2E 3
- Ubiquitin-Conjugating Enzyme E2G 2
- Ubiquitin-Conjugating Enzyme E2I
- Ubiquitin-Conjugating Enzyme E2K
- Ubiquitin-Conjugating Enzyme E2N
- Ubiquitin-Conjugating Enzyme E2S
- UBL3
- UBL4A
- UBL4B
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