Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Ubiquilin 2 Produits

(Ubiquilin 2 (UBQLN2))
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases\; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein. [provided by RefSeq, Oct 2009].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories Ubiquilin 2 en vedette

Ubiquilin 2 Anticorps

High quality antibodies with extensive validation data.

Ubiquilin 2 Kits ELISA

Reliable ELISA kits for a wide range of species.

Ubiquilin 2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Ubiquilin 2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (11)
  • (7)
N° du produit ABIN565449
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6149859
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7174228
Quantité 100 μg
Fiche technique Fiche technique

Ubiquilin 2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971032
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960336
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5591997
Quantité 96 tests
Fiche technique Fiche technique

Ubiquilin 2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324460
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324462
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125571
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Ubiquilin 2

Alexander, Ghanbari Niaki, Zhang, Sarkar, Liu, Nirujogi, Pandey, Myong, Wang: "Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 49, pp. E11485-E11494, (2019) (PubMed).

Sharkey, Safren, Pithadia, Gerson, Dulchavsky, Fischer, Patel, Lantis, Ashraf, Kim, Meliki, Minakawa, Barmada, Ivanova, Paulson: "Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 44, pp. E10495-E10504, (2018) (PubMed).

Yau, Doerner, Castellanos, Haakonsen, Werner, Wang, Yang, Martinez-Martin, Matsumoto, Dixit, Rape: "Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control." dans: Cell, Vol. 171, Issue 4, pp. 918-933.e20, (2017) (PubMed).

Hjerpe, Bett, Keuss, Solovyova, McWilliams, Johnson, Sahu, Varghese, Wood, Wightman, Osborne, Bates, Glickman, Trost, Knebel, Marchesi, Kurz: "UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome." dans: Cell, Vol. 166, Issue 4, pp. 935-49, (2016) (PubMed).

Le, Chang, Kovlyagina, Georgiou, Safren, Braunstein, Kvarta, Van Dyke, LeGates, Philips, Morrison, Thompson, Puche, Gould, Rothstein, Wong, Monteiro: "Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 47, pp. E7580-E7589, (2016) (PubMed).

Riku, Watanabe, Yoshida, Mimuro, Iwasaki, Masuda, Ishigaki, Katsuno, Sobue: "Marked Involvement of the Striatal Efferent System in TAR DNA-Binding Protein 43 kDa-Related Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis." dans: Journal of neuropathology and experimental neurology, (2016) (PubMed).

Porta, Kwong, Trojanowski, Lee: "Drosha inclusions are new components of dipeptide-repeat protein aggregates in FTLD-TDP and ALS C9orf72 expansion cases." dans: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 380-7, (2015) (PubMed).

Zeng, Wang, Merillat, N Minakawa, Perkins, Ramani, Tallaksen-Greene, Costa, Albin, Paulson: "Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3." dans: Neurobiology of disease, Vol. 82, pp. 281-8, (2015) (PubMed).

Ceballos-Diaz, Rosario, Park, Chakrabarty, Sacino, Cruz, Siemienski, Lara, Moran, Ravelo, Golde, McFarland: "Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice." dans: Molecular neurodegeneration, Vol. 10, pp. 25, (2015) (PubMed).

Satoh, Tabunoki, Ishida, Saito, Arima: "Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains." dans: Neuropathology and applied neurobiology, Vol. 39, Issue 7, pp. 817-30, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à Ubiquilin 2

ubiquilin 2 (UBQLN2), ubiquilin 2 (Ubqln2), ALS15, CHAP1, Chap1, DSK2, Dsk2, HRIHFB2157, N4BP4, Plic-2, PLIC2, Plic2, RGD1563566, UBQLN2

Protein level used designations for Ubiquilin 2

  • Nedd4 binding protein 4
  • protein linking IAP with cytoskeleton 2
  • ubiquilin-2
  • ubiquitin-like product Chap1/Dsk2
  • Ubiquitin-related protein
  • ubiquilin 2
Vous êtes ici:
Support technique