The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Dernières publications pour nos Ubiquitin-Conjugating Enzyme E2I Protéines
Tachibana, Iwata, Watanabe, Nobukuni, Ploplis, Kajigaya: "Assignment of the gene for a ubiquitin-conjugating enzyme (UBE2I) to human chromosome band 16p13.3 by in situ hybridization." dans: Cytogenetics and cell genetics, Vol. 75, Issue 4, pp. 222-3, (1997) (PubMed).
Watanabe, Fujiwara, Kawai, Shimizu, Takami, Hirano, Okuno, Ozaki, Takeda, Shimada, Nagata, Takaichi, Takahashi, Nakamura, Shin: "Cloning, expression, and mapping of UBE2I, a novel gene encoding a human homologue of yeast ubiquitin-conjugating enzymes which are critical for regulating the cell cycle." dans: Cytogenetics and cell genetics, Vol. 72, Issue 1, pp. 86-9, (1996) (PubMed).
Yasugi, Howley: "Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9." dans: Nucleic acids research, Vol. 24, Issue 11, pp. 2005-10, (1996) (PubMed).
Pseudonymes pour Ubiquitin-Conjugating Enzyme E2I Protéines