UGT1A1 Produits
(UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))
Catégories
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008].
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Catégories UGT1A1 en vedette
UGT1A1 Anticorps
High quality antibodies with extensive validation data.
UGT1A1 Kits ELISA
Reliable ELISA kits for a wide range of species.
UGT1A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
UGT1A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (6)
N° du produit
ABIN6149895
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (4)
N° du produit
ABIN7262012
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (5)
N° du produit
ABIN5693290
Quantité
100 μg
Fiche technique
Fiche technique
UGT1A1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960358
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6975305
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6960359
Quantité
96 tests
Fiche technique
Fiche technique
UGT1A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1324569
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3113166
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7408798
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits UGT1A1
: "A Practical and High-Affinity Fluorescent Probe for Uridine Diphosphate Glucuronosyltransferase 1A1: A Good Surrogate for Bilirubin." dans: Journal of medicinal chemistry, Vol. 60, Issue 23, pp. 9664-9675, (2017) (PubMed).: "Phenethyl isothiocyanate and indole-3-carbinol from cruciferous vegetables, but not furanocoumarins from apiaceous vegetables, reduced PhIP-induced DNA adducts in Wistar rats." dans: Molecular nutrition & food research, Vol. 60, Issue 9, pp. 1956-66, (2016) (PubMed).
: "Apiaceous vegetable consumption decreases PhIP-induced DNA adducts and increases methylated PhIP metabolites in the urine metabolome in rats." dans: The Journal of nutrition, Vol. 145, Issue 3, pp. 442-51, (2015) (PubMed).
: "Fenofibrate pre-treatment suppressed inflammation by activating phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling in renal ischemia-reperfusion injury." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 35, Issue 1, pp. 58-63, (2015) (PubMed).
: "Danning tablets attenuates ?-naphthylisothiocyanate-induced cholestasis by modulating the expression of transporters and metabolic enzymes." dans: BMC complementary and alternative medicine, Vol. 14, pp. 249, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à UGT1A1
UDP glucuronosyltransferase family 1 member A1 (UGT1A1), UDP glucuronosyltransferase 1 family, polypeptide A1 (Ugt1a1), UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1), UDP-glucuronosyltransferase 1-1 (LOC100065342), UDP-glucuronosyltransferase (LOC100125517), UDP-glucuronosyltransferase 1-1 (LOC100229734), UDP-glucuronosyltransferase 1-6 (LOC100405984), UDP-glucuronosyltransferase 1-1 (LOC100511479), UDP glucuronosyltransferase family 1 member A1 (Ugt1a1), UDP glucuronosyltransferase 1 family polypeptide a1 (ugt1a1), BILIQTL1, GNT1, Gnt1, HUG-BR1, UDPGT, Udpgt, Udpgt-1a, UDPGT 1-1, UGT1, Ugt1, UGT1A, UGT1A01, UgtBr1, zgc:123097Protein level used designations for UGT1A1
- UDP glycosyltransferase 1 family, polypeptide A1
- UDP-glucuronosyltransferase 1-1
- UDP-glucuronosyltransferase 1-A
- UDP-glucuronosyltransferase 1A1
- UGT-1A
- UGT1*1
- UGT1-01
- UGT1.1
- bilirubin UDP-glucuronosyltransferase 1-1
- bilirubin UDP-glucuronosyltransferase isozyme 1
- bilirubin-specific UDPGT isozyme 1
- UDP-glucuronosyltransferase 1 family, member 1
- UDP-glucuronosyltransferase 1 family, polypeptide A1
- UDPGT
- UDP glucuronosyltransferase 1 family, polypeptide A1
- uridine diphosphate glucuronosyltransferase 1A1
- UDP-glucuronosyltransferase UGT1A01
- UDP glucuronosyltransferase 1 family polypeptide A1
- UDP glycosyl transferase 1A1
- UDP-glucuronosyltransferase 1-1-like
- B1
- UDP-glucuronosyltransferase 1 family member 1
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