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USP5 Produits

(Ubiquitin Specific Peptidase 5 (USP5))

Catégories

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010].

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Catégories USP5 en vedette

USP5 Anticorps

High quality antibodies with extensive validation data.

USP5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

USP5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN1683231
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Dog, Human, Monkey, Rat
Application WB, IHC, IHC (p)
Validations
  • (9)
N° du produit ABIN1501693
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN2856099
Quantité 100 μL
Fiche technique Fiche technique

USP5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6232800
Quantité 96 tests
Fiche technique Fiche technique

USP5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125597
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324831
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1324833
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits USP5

Yoshioka, Ye, Okada, Taniguchi, Yoshida, Sugaya, Onose, Koshino, Takahashi, Yajima, Yajima, Abe: "Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-α production in RBL-2H3 cells." dans: PLoS ONE, Vol. 8, Issue 12, pp. e80931, (2013) (PubMed).

Ouyang, Ali, Ravichandran, Dong, Qiu, MacKenzie, Dhe-Paganon, Arrowsmith, Zhai: "Protein aggregates are recruited to aggresome by histone deacetylase 6 via unanchored ubiquitin C termini." dans: The Journal of biological chemistry, Vol. 287, Issue 4, pp. 2317-27, (2012) (PubMed).

Reverdy, Conrath, Lopez, Planquette, Atmanene, Collura, Harpon, Battaglia, Vivat, Sippl, Colland: "Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme." dans: Chemistry & biology, Vol. 19, Issue 4, pp. 467-77, (2012) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Falquet, Paquet, Frutiger, Hughes, Hoang-Van, Jaton: "cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2)." dans: FEBS letters, Vol. 376, Issue 3, pp. 233-7, (1996) (PubMed).

Falquet, Paquet, Frutiger, Hughes, Hoang-Van, Jaton: "A human de-ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro." dans: FEBS letters, Vol. 359, Issue 1, pp. 73-7, (1995) (PubMed).

Synonymes et noms alternatifs relatifs à USP5

ubiquitin specific peptidase 5 (USP5), ubiquitin carboxyl-terminal hydrolase 5 (CNH02890), ubiquitin carboxyl-terminal hydrolase 5 (EHI_049940), ubiquitin carboxyl-terminal hydrolase 5 (CC1G_12961), ubiquitin carboxyl-terminal hydrolase 5 (MCYG_01862), ubiquitin carboxyl-terminal hydrolase 5, putative (CGB_L3600C), ubiquitin specific protease 5 (PY00546), ubiquitin specific peptidase 5 (isopeptidase T) (Usp5), ubiquitin specific peptidase 5 (Usp5), AA407472, ISOT, ISOT-1, Ucht

Protein level used designations for USP5

  • ubiquitin carboxyl-terminal hydrolase 5
  • Ubiquitin isopeptidase T
  • ubiquitin specific peptidase 5 (isopeptidase T) isoform 1
  • ubiquitin specific peptidase 5 (isopeptidase T) isoform 2
  • ubiquitin specific protease 5
  • ubiquitin specific peptidase 5
  • deubiquitinating enzyme 5
  • isopeptidase T
  • ubiquitin isopeptidase T
  • ubiquitin specific protease 5 (isopeptidase T)
  • ubiquitin thioesterase 5
  • ubiquitin thiolesterase 5
  • ubiquitin-specific protease-5 (ubiquitin isopeptidase T)
  • ubiquitin-specific-processing protease 5
  • ubiquitin carboxy terminal hydrolase T
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