CrkL anticorps (pTry207)
Aperçu rapide pour CrkL anticorps (pTry207) (ABIN645839)
Antigène
Voir toutes CrkL (CRKL) AnticorpsReactivité
Hôte
Conjugué
Application
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Épitope
- pTry207
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Specificité
- The Goat anti-CRKL antibody detects protein derived from human recombinant protein and K562 lysate at various concentrations.
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Réactivité croisée
- Humain, Souris, Rat (Rattus)
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Attributs du produit
- Goat Anti-CRKL
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Immunogène
- Synthetic peptide with sequence C-KIFDPQNPDENE, from the C Terminus of the protein sequence according to NP_005198, was used as immunogen.
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Isotype
- IgG
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Restrictions
- For Research Use only
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Reconstitution
- Supplied as 100µg of purified antibody 0.5mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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Stock
- -20 °C
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- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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Autre désignation
- CRKL
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Sujet
- Anti-Crkl antibody is a 33kDa adaptor protein that has been shown to activate the RAS and JUN kinase signalling pathways. Also transforms fibroblasts in a RAS dependant manner. Crkl is a substitute of BCR ABL tyrosine kinase. In addition, Crkl has oncogenic potential, and may mediate the transduction of intracellular signals.
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NCBI Accession
- NP_005198
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Pathways
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor
Antigène
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