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CDKN1B anticorps (Internal Region)

Name: CDKN1B anticorps (Internal Region)
SKU: ABIN374656
Availability: InStock

Cet anticorps Chèvre Polyclonal détecte spécifiquement CDKN1B dans WB. Il présente une réactivité avec des échantillons de Humain, Chien et Cat.

Image no. 1 for anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (Internal Region) antibody (ABIN374656) (CDKN1B anticorps (Internal Region))

1 image

N° du produit ABIN374656

772,31 €

Plus frais de livraison 40,00 € et TVA

0.1 mg

Destination: France

Envoi sous 17 jours ouvrables

Aperçu rapide pour CDKN1B anticorps (Internal Region) (ABIN374656)

Antigène

Voir toutes CDKN1B Anticorps

CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Reactivité

Humain, Chien, Cat

Hôte

Chèvre

Clonalité

Polyclonal

Conjugué

Cet anticorp CDKN1B est non-conjugé

Application

Western Blotting (WB)

Discover our top product CDKN1B Anticorps primaire

Épitope
33

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Internal Region

Specificité

This antibody reacts to CDKN1B.

Réactivité croisée (Details)

Species reactivity (expected):Feline, Canine.
Species reactivity (tested):Human.

Purification

Affinity chromatography

Immunogène

Peptide with sequence C-KRPATDDSSTQNK, from the internal region of the protein sequence
anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (AA 1-198) antibody
CDKN1B Reactivité: Humain WB, ELISA, IF, IHC (p), PLA Hôte: Souris Monoclonal 4B4-E6 unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (AA 150-198) antibody
CDKN1B Reactivité: Humain, Souris, Rat WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
KO Validated CDKN1B Reactivité: Humain WB, IHC, IF, IHC (p), IP, ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
CDKN1B Reactivité: Humain, Souris, Rat, Singe WB, IHC, IF, FACS Hôte: Souris Monoclonal SX53G8 unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
KD Validated CDKN1B Reactivité: Humain WB, FACS, ICC Hôte: Lapin Monoclonal 23GB1825 unconjugated Recombinant Antibody

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
CDKN1B Reactivité: Humain, Souris, Rat WB, IF, FACS, IHC (p) Hôte: Souris Monoclonal DCS-72-F6-KIP1-769 unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (AA 1-198) antibody
CDKN1B Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (pThr187) antibody
CDKN1B Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
CDKN1B Reactivité: Humain, Souris, Rat, Singe WB, IHC, IF, FACS Hôte: Souris Monoclonal DCS-72-F6 unconjugated

anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
CDKN1B Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Monoclonal 1G2 unconjugated Recombinant Antibody

Indications d'application

Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freezing and thawing.

Stock

4 °C/-20 °C

Stockage commentaire

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène

CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Autre désignation

CDKN1B / KIP1

Sujet

Cell cycle progression is regulated by cyclins and their cognate Cdks. p27 KIP 1 is a cell cycle regulatory mitotic inhibitor of cdk activity. p27 KIP 1 is a candidate tumor suppressor gene, and has been proposed to function as a possible mediator of TGF beta induced G1 arrest. p27 KIP 1 is up regulated in response to antimitogenic stimuli. The increased protein expression of p27 results in cellular arrest by binding to cyclin/Cdk complexes such as cyclin D1/Cdk4. p27 Kip1 is regulated by phosphorylation on serine 10 (S10) and threonine 187 (T187). Phosphorylation by CDK2 on T187 results in ubiquitylation and degradation of p27 Kip 1, while phosphorylation by hKIS on S10 signals the nuclear export to the cytoplasm.Synonyms: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1

ID gène

1027, 9606

UniProt

P46527

Pathways

Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy