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NLRP3 anticorps (AA 82-93)

Cet anticorps anti-NLRP3 Polyclonal Chèvre (ABIN297366) détecte spécifiquement NLRP3 dans ELISA, IHC et IHC (p). L’anticorps est réactif avec des échantillons de Humain et Singe.
N° du produit ABIN297366
639,37 €
Plus frais de livraison 40,00 € et TVA
50 μg
Destination: France
Envoi sous 15 à 20 jours ouvrables

Aperçu rapide pour NLRP3 anticorps (AA 82-93) (ABIN297366)

Antigène

Voir toutes NLRP3 Anticorps
NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

Reactivité

  • 106
  • 47
  • 33
  • 15
  • 5
  • 3
  • 1
  • 1
  • 1
Humain, Singe

Hôte

  • 97
  • 18
  • 2
Chèvre

Clonalité

  • 79
  • 38
Polyclonal

Conjugué

  • 60
  • 10
  • 7
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp NLRP3 est non-conjugé

Application

  • 70
  • 42
  • 28
  • 26
  • 21
  • 18
  • 12
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 82-93

    Specificité

    Human NLRP3. This antibody is expected to recognise all five reported isoforms (NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1). Reported variants represent identical protein (NP_004886.3 and NP_001073289.1).

    Homologie

    Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Bat, Panda, Pig (92%) Dog, Bovine, Rabbit (83%).

    Purification

    Immunoaffinity purified

    Immunogène

    Synthetic peptide C-DLYEKAKRDEPK from an internal region of human NLRP3 (NP_004886.3, NP_899632.1, NP_001230062.1, NP_001120933.1, NP_001120934.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Bat, Panda, Pig (92%), Dog, Bovine, Rabbit (83%).

    Type of Immunogen: Synthetic peptide
  • Indications d'application

    Approved: IHC, IHC-P (2.5 μg/mL), Peptide-ELISA (1:64000)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Minimize freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze-thaw cycles.
  • Antigène

    NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))

    Autre désignation

    NALP3 / NLRP3

    Sujet

    Name/Gene ID: NLRP3

    Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS

    ID gène

    114548

    NCBI Accession

    NP_004886, NP_899632, NP_001230062, NP_001120933, NP_001120934

    UniProt

    Q96P20

    Pathways

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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