OGG1 anticorps (Internal Region)
Aperçu rapide pour OGG1 anticorps (Internal Region) (ABIN372767)
Antigène
Voir toutes OGG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Internal Region
-
Specificité
- Recognizes 8-oxoguanine DNA Glycosylase Homolog 1 (OGG1).
-
Réactivité croisée (Details)
-
Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat. -
Purification
- Immunoaffinity Chromatography.
-
Immunogène
- Synthetic peptide (C-HPKTSQAKGPSPLANK) from an Internal region of Mouse OGG1.
-
Isotype
- IgG
-
-
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-100), (N-Term) antibody
OGG1 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IP, ICC, IF Hôte: Lapin Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 31-345) antibodyOGG1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-324) antibodyOGG1 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-324) antibodyOGG1 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 151-250) antibodyOGG1 Reactivité: Humain, Souris, Rat WB, ELISA, FACS, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-345) antibodyOGG1 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) antibodyOGG1 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (Internal Region) antibodyVerified OGG1 Reactivité: Humain, Rat WB, IHC, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) antibodyOGG1 Reactivité: Humain WB, IHC Hôte: Souris Monoclonal CPTC-OGG1-1 unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 318-345), (C-Term) antibodyOGG1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB21522 unconjugated
-
-
Indications d'application
-
ELISA: 1/28000. Western Blot: 0.1-0.3 μg/mL. Immunohistochemistry on Paraffin Sections: 2.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- Tris Saline Buffer, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
-
Autre désignation
- OGG1
-
Sujet
- The Ogg1 gene encodes a DNA repair enzyme (N glycosylase/DNA lyase) that incises DNA at 8 oxoG residues. N glycosylase/DNA lyase excises 7,8 dihydro 8 oxoguanine and 2,6 diamino 4 hydroxy 5 N methylformamidopyrimidine (FAPY) from damaged DNA. N glycosylase/DNA lyase has a beta lyase activity that nicks DNA 3' to the lesion. Alternative splicing of the C terminal region of the Ogg1 gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N terminal region in common. Many alternative splice variants for this gene have been described, but the full length nature for every variant has not been determined. The N terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.Synonyms: MMH, MUTM, N-glycosylase/DNA lyase, OGH1
-
ID gène
- 81528
-
NCBI Accession
- NP_110497
-
UniProt
- O70249
-
Pathways
- Réparation de l'ADN
Antigène
-
