DcR2 anticorps (N-Term)
Aperçu rapide pour DcR2 anticorps (N-Term) (ABIN238513)
Antigène
Voir toutes DcR2 (TNFRSF10D) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-210, N-Term
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Specificité
- This antibody reacts with TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Attributs du produit
- Synonyms: TNFRSF10D, DCR2, TRAIL-R4, TRUNDD, Decoy receptor 2, TRAIL receptor 4, Tumor necrosisfactor receptor superfamily member 10D, TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor with a truncated death domain
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Purification
- Protein A affinity chromatography
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Immunogène
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein.
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Isotype
- IgG1
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibody
TNFRSF10D Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibodyTNFRSF10D Reactivité: Humain, Singe WB, ELISA Hôte: Souris Monoclonal 7G7H9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 56-211) antibodyTNFRSF10D Reactivité: Humain, Souris WB, ELISA Hôte: Souris Monoclonal 6G7G1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 257-386) antibodyTNFRSF10D Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (FITC)TNFRSF10D Reactivité: Humain FACS Hôte: Souris Monoclonal TRAIL-R4-01 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibodyTNFRSF10D Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 252-278) antibodyTNFRSF10D Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB24080 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 249-263) antibodyTNFRSF10D Reactivité: Humain, Souris, Rat WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) antibodyTNFRSF10D Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB4685 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D) (AA 1-210) antibody (APC)TNFRSF10D Reactivité: Humain FACS Hôte: Souris Monoclonal TRAIL-R4-01 APC
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Indications d'application
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Suitable for use in Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 without preservatives
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Agent conservateur
- Without preservative
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
Shelf life: One year from despatch. -
Date de péremption
- 12 months
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- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
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Autre désignation
- CD264 / TRAILR4
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Sujet
- TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).Synonyms: DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRAIL-R4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D
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ID gène
- 8793
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UniProt
- Q9UBN6
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Pathways
- Apoptose
Antigène
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