TRIM anticorps (Intracellular) (PE)
(1 reference)Aperçu rapide pour TRIM anticorps (Intracellular) (PE) (ABIN125716)
Antigène
Voir toutes TRIM (TRAT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 29-186, Intracellular
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Fonction
- Anti-TRIM PE
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Aucune reactivité croisée
- Souris
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Réactivité croisée (Details)
- Human
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Attributs du produit
- The antibody TRIM-04 recognizes an intracellular epitope of T cell receptor-interacting molecule (TRIM), a 30 kDa adaptor protein expressed by T cells.
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Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogène
- Recombinant intracellular domain (aa 29-186) of human TRIM.
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Isotype
- IgG2a
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anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 29-186), (Intracellular) antibody
TRAT1 Reactivité: Humain WB, IP, ICFC Hôte: Souris Monoclonal TRIM-04 unconjugated
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 29-186) antibodyTRAT1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 98-127) antibodyTRAT1 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal RB30370 unconjugated
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 29-186) antibodyTRAT1 Reactivité: Humain, Souris WB, FACS, IF Hôte: Souris Monoclonal TRIM-4 unconjugated
anti-T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1) (AA 25-186) antibodyTRAT1 Reactivité: Humain ELISA, WB, FACS Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze,Protect from prolonged exposure to light
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain." dans: The Journal of experimental medicine, Vol. 193, Issue 11, pp. 1269-84, (2001) (PubMed).
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- TRIM (TRAT1) (T Cell Receptor Associated Transmembrane Adaptor 1 (TRAT1))
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Autre désignation
- TRIM
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Sujet
- T cell receptor associated transmembrane adaptor 1,TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.,TRAT, TCRIM
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ID gène
- 50852
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UniProt
- Q6PIZ9
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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