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TR4 anticorps (N-Term)

L’anticorps anti-TR4 Polyclonal Lapin est utilisé pour la détection de TR4 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cheval et Cobaye. Il a été validé pour WB.
N° du produit ABIN502652
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour TR4 anticorps (N-Term) (ABIN502652)

Antigène

Voir toutes TR4 (NR2C2) Anticorps
TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

Reactivité

  • 163
  • 113
  • 103
  • 8
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye

Hôte

  • 169
  • 12
  • 1
Lapin

Clonalité

  • 150
  • 32
Polyclonal

Conjugué

  • 71
  • 9
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
Cet anticorp TR4 est non-conjugé

Application

  • 136
  • 66
  • 66
  • 47
  • 34
  • 28
  • 25
  • 21
  • 16
  • 13
  • 6
  • 1
Western Blotting (WB)
  • Épitope

    • 40
    • 39
    • 15
    • 15
    • 11
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    INKHHRNRCQ FCRLKKCLEM GMKMESVQSE RKPFDVQREK PSNCAASTEK

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Attributs du produit

    This is a rabbit polyclonal antibody against NR2C2. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human NR2C2
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 615 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))

    Autre désignation

    NR2C2

    Sujet

    Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: TAK1, TR2R1, TR4, hTAK1
    Protein Interaction Partner: VPRBP, CUL4B, UBC, DDB1, KDM1A, NR2C2, HSP90AA1, JAZF1, TAB2, TRAF6, PELI1, PELI2, RBCK1, PDLIM7, TAB1, TRIM28, MTA1, HDAC3, NR2C1, RBBP4, HDAC1, DNMT1, CHD4, Cebpb, ITSN2, CD2AP, RXRB, NR2C2AP, PEBP1, HSP90AB1, CDC37, IKBKB, FKBP5, TRAF2, CHUK, HNF4A, AR
    Protein Size: 615

    Poids moléculaire

    67 kDa

    ID gène

    7182

    NCBI Accession

    NM_003298, NP_003289

    UniProt

    P49116

    Pathways

    TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
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