RPS6KA2 anticorps (Middle Region)
Aperçu rapide pour RPS6KA2 anticorps (Middle Region) (ABIN503865)
Antigène
Voir toutes RPS6KA2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LSRQDVHLVK GAMAATYFAL NRTPQAPRLE PVLSSNLAQR RGMKRLTSTR
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against RPS6KA2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RPS6KA2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 733 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
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Autre désignation
- RPS6KA2
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Sujet
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RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3
Protein Interaction Partner: MAPK3, MAPK1, RPS6KA1, HSP90AA1, FLNC, CSNK2B, STXBP2, NQO2, UBC, RPS6KA2, JUN, FOS, SHANK1, BAD, MAGI1, L1CAM, MAP2K1, CREB1, CREBBP,
Protein Size: 733 -
Poids moléculaire
- 81 kDa
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ID gène
- 6196
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NCBI Accession
- NM_021135, NP_066958
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UniProt
- Q15349
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades
Antigène
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