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PRKAB1 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement PRKAB1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Souris.
N° du produit ABIN391054
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour PRKAB1 anticorps (N-Term) (ABIN391054)

Antigène

Voir toutes PRKAB1 Anticorps
PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Reactivité

  • 129
  • 112
  • 108
  • 8
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Souris

Hôte

  • 150
  • 11
Lapin

Clonalité

  • 130
  • 31
Polyclonal

Conjugué

  • 59
  • 9
  • 8
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Cet anticorp PRKAB1 est non-conjugé

Application

  • 98
  • 65
  • 65
  • 51
  • 36
  • 25
  • 19
  • 18
  • 15
  • 9
  • 6
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB3228
  • Épitope

    • 21
    • 15
    • 15
    • 15
    • 15
    • 10
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4-34, N-Term

    Homologie

    Rat

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This AMPK beta (PRKAB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human AMPK beta (PRKAB1).

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Antigène

    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

    Autre désignation

    AMPK beta (PRKAB1)

    Sujet

    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

    Poids moléculaire

    30382

    ID gène

    5564

    NCBI Accession

    NP_006244

    UniProt

    Q9Y478

    Pathways

    AMPK Signaling, L'effet Warburg
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