TNFRSF10B anticorps
Aperçu rapide pour TNFRSF10B anticorps (ABIN376980)
Antigène
Voir toutes TNFRSF10B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Human DR5
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Attributs du produit
- Rabbit Anti-Human DR5-UNLB
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Purification
- Purified
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Immunogène
- Recombinant DR5
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Isotype
- IgG
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 234-435) antibody
TNFRSF10B Reactivité: Humain WB, IHC, ICC, IF Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 233-440) antibodyTNFRSF10B Reactivité: Humain, Souris, Rat WB, FACS, IHC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibodyTNFRSF10B Reactivité: Humain WB, IHC, IF Hôte: Lapin Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 1-440) antibodyTNFRSF10B Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 71-170) antibodyTNFRSF10B Reactivité: Humain WB, ELISA, IP Hôte: Souris Monoclonal 2D6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (N-Term) antibodyTNFRSF10B Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 56-210) antibodyTNFRSF10B Reactivité: Humain ELISA Hôte: Souris Monoclonal 2H5B8 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 266-393) antibodyTNFRSF10B Reactivité: Humain IHC Hôte: Souris Monoclonal DR5-3381 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) antibodyTNFRSF10B Reactivité: Humain, Souris WB, ICC Hôte: Souris Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B) (AA 301-381) antibodyTNFRSF10B Reactivité: Humain WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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- Applications: FC - Quality tested WB , ICC
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L Immunoblotting Purified (UNLB) antibody 2 g/mL Immunocytochemistry Purified (UNLB) antibody 2 g/mL
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Commentaires
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induction of apoptosis
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Volume d'échantillon
- 0,2 mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 0.1 mg of purified immunoglobulin in 0.2 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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Autre désignation
- DR5
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Sujet
- DR5, also known as TRAIL-R2, TRICK2 and KILLER, is a widely expressed type I membrane member of the tumor necrosis (TNF) receptor family. Members of this family contain multiple cysteine-rich repeats in their extracellular domain and while the cytoplasmic region is less conserved, they do contain an intracellular 80 AA motif known as the ‘death domain' (DD). DR5 is a receptor for the cytotoxic ligand TRAIL which induces apoptosis and it is the cytoplasmic DD that is responsible for transducing the death process. DR5 has also been shown to activate NF- λB.
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Pathways
- Signalisation p53, Apoptose, Positive Regulation of Endopeptidase Activity
Antigène
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