IKKi/IKKe anticorps (C-Term)
Aperçu rapide pour IKKi/IKKe anticorps (C-Term) (ABIN360635)
Antigène
Voir toutes IKKi/IKKe (IKBKE) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody reacts to IKKE.
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Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human IKKE.
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Isotype
- Ig Fraction
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anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 495-716) antibody
IKBKE Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (C-Term) antibodyIKBKE Reactivité: Humain, Souris, Rat WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 686-716), (C-Term) antibodyIKBKE Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB3912 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 541-640) antibodyIKBKE Reactivité: Humain ELISA, IHC (p) Hôte: Souris Monoclonal 1F7 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 544-680) antibodyIKBKE Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 1-257) antibodyIKBKE Reactivité: Humain ELISA Hôte: Souris Monoclonal 6B4B5 unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) antibodyIKBKE Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB2720 unconjugated Recombinant Antibody
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) antibodyIKBKE Reactivité: Humain WB, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (AA 686-716) antibodyIKBKE Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE) (pSer172) antibodyIKBKE Reactivité: Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))
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Autre désignation
- IKBKE / IKKE
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Sujet
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).Synonyms: I kappa-B kinase epsilon, IKK-E, IKK-I, IKK-epsilon, IKKI, Inducible I kappa-B kinase, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, KIAA0151
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ID gène
- 9641, 9606
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UniProt
- Q14164
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Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Antigène
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