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MAP4K1 anticorps (C-Term)

Cet anticorps anti-MAP4K1 Polyclonal Lapin (Clone RB1208) (ABIN392502) détecte spécifiquement MAP4K1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.
N° du produit ABIN392502
434,77 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour MAP4K1 anticorps (C-Term) (ABIN392502)

Antigène

Voir toutes MAP4K1 Anticorps
MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

Reactivité

  • 65
  • 12
  • 10
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 61
  • 5
  • 1
Lapin

Clonalité

  • 63
  • 4
Polyclonal

Conjugué

  • 36
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MAP4K1 est non-conjugé

Application

  • 51
  • 27
  • 19
  • 14
  • 14
  • 11
  • 8
  • 7
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB1208
  • Épitope

    • 16
    • 10
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-350, C-Term

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogène

    This MAP4K1 (HPK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-350 amino acids from the C-terminal region of human MAP4K1 (HPK1).

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Antigène

    MAP4K1 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1))

    Autre désignation

    MAP4K1 (HPK1)

    Sujet

    Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

    Poids moléculaire

    91296

    ID gène

    11184

    NCBI Accession

    NP_001036065, NP_009112

    UniProt

    Q92918

    Pathways

    TCR Signaling, Signaling of Hepatocyte Growth Factor Receptor
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