NEK9 anticorps (C-Term)
Aperçu rapide pour NEK9 anticorps (C-Term) (ABIN392654)
Antigène
Voir toutes NEK9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 846-877, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This NEK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-877 amino acids from the C-terminal region of human NEK9.
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Isotype
- Ig Fraction
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anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 226-326) antibody
NEK9 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 1F6 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyKD Validated NEK9 Reactivité: Humain WB, FACS Hôte: Souris Monoclonal 24GB6355 unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 730-979) antibodyNEK9 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyNEK9 Reactivité: Humain, Souris, Rat WB, IF (p), IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (Internal Region) antibodyNEK9 Reactivité: Humain, Souris WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 821-979) antibodyNEK9 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) antibodyNEK9 Reactivité: Humain, Cheval, Lapin, Porc, Singe, Hamster IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (Kinase Domain) antibodyNEK9 Reactivité: Humain, Souris, Cheval, Lapin, Boeuf (Vache), Porc, Singe, Roussette (Chauve-souris), Poulet IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 1-979) antibodyNEK9 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) (AA 1-979) antibodyNEK9 Reactivité: Humain IP Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- WB: 1:1000. IHC-P: 1:50~100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- NEK9 (NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9))
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Autre désignation
- NEK9
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Sujet
- NEK9, a member of the NIMA subfamily of Ser/Thr protein kinases, is a pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. It phosphorylates different histones (serine and threonine residues on H3), myelin basic protein, beta-casein (serine residues), and BICD2. NEK9 is activated during mitosis by intramolecular autophosphorylation. Activity and autophosphorylation is activated by manganese >> magnesium ions, and is sensitive to increasing concentration of detergents. This protein is not cell-cycle regulated but activity is higher in G0-arrested cells. NEK is part of a homodimer that binds to Ran GTPase, and exhibits a greater affinity for Ran-GDP over Ran-GTP. Interaction is also noted with NEK6 and NEK7 family members. This cytoplasmic protein is most abundant in heart, liver, kidney and testis, and is also expressed in smooth muscle cells and fibroblasts. Expression varies mildly across the cell cycle, with highest expression observed in G1 and stationary-phase cells.
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Poids moléculaire
- 107168
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ID gène
- 91754
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NCBI Accession
- NP_149107
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UniProt
- Q8TD19
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Pathways
- SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
Antigène
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