PDE4D anticorps
Aperçu rapide pour PDE4D anticorps (ABIN272057)
Antigène
Voir toutes PDE4D AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- Thhis antibody detects endogenous levels of PDE4D protein. (region surrounding His47)
-
Réactivité croisée (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Pureté
- > 95 % pure by SDS-PAGE
-
-
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibody
Verified PDE4D Reactivité: Humain WB, ELISA, IHC, EIA Hôte: Chèvre Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 466-709) antibodyPDE4D Reactivité: Humain, Souris, Rat WB, ELISA, IHC, FACS, ICC Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 164-213) antibodyPDE4D Reactivité: Humain, Souris, Rat, Cheval, Poulet, Porc, Singe, Xenopus laevis WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibodyPDE4D Reactivité: Humain WB, ICC, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) antibodyPDE4D Reactivité: Humain, Rat WB, IF Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibodyPDE4D Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) antibodyPDE4D Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 24GB4095 unconjugated Recombinant Antibody
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 581-809) antibodyPDE4D Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (N-Term) antibodyPDE4D Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
-
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
-
Autre désignation
- PDE4D
-
Sujet
- Phosphodiesterases (PDE) hydrolyze cAMP to 5'AMP and thus play a critical role in the regulation of intracellular cAMP. Division of the PDE superfamily by sequence homology and enzymatic properties yields 11 PDE families. A unique upstream conserved region (UCR) characterizes the PDE4 family. Four separate genes (A-D) encode the PDE4 enzymes, and alternative splicing generates short or long isoforms of each gene. Long PDE4 isoforms contain both UCR1 and UCR2 while short PDE4 isoforms possess only UCR2. Both UCR domains are necessary for dimerization of PDE4 isoforms. The human PDE4D gene maps to chromosome 5q12. The splice variants include isoforms PDE4D1-6.Synonyms: 5'-cyclic phosphodiesterase 4D, DPDE3, EC=3.1.4.17, PDE43, PDE4D, cAMP-specific 3'
-
Poids moléculaire
- approx. 88 kDa
-
ID gène
- 5144
-
NCBI Accession
- NP_001098101
-
UniProt
- Q08499
-
Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
-
