TNFRSF10B anticorps (AA 388-407)
Aperçu rapide pour TNFRSF10B anticorps (AA 388-407) (ABIN290834)
Antigène
Voir toutes TNFRSF10B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 388-407
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Specificité
- A peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor. The same sequence is found in isoform 1 at amino acids 417-436.
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Purification
- Protein G purified
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Immunogène
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A peptide corresponding to amino acids 388 to 407 (isoform 2) of human DR5 precursor (1,2). The same sequence is found in isoform 1 at amino acids 417-436.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Indications d'application
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Approved: Flo, ICC, IHC, IHC-P (10 μg/mL), WB (1:500 - 1:1000)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- avoid freeze thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
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Autre désignation
- TNFRSF10B / Killer / DR5
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Sujet
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Name/Gene ID: TNFRSF10B
Family: TNF Receptor
Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9 -
ID gène
- 8795
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UniProt
- O14763
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Pathways
- Signalisation p53, Apoptose, Positive Regulation of Endopeptidase Activity
Antigène
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