WASF1 anticorps
Aperçu rapide pour WASF1 anticorps (ABIN272093)
Antigène
Voir toutes WASF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of WAVE1 protein. (region surrounding Ile119)
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Pureté
- > 95 % pure by SDS-PAGE
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anti-WAS Protein Family, Member 1 (WASF1) (AA 381-553) antibody
WASF1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (Internal Region) antibodyWASF1 Reactivité: Humain, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) antibodyWASF1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB4605 unconjugated Recombinant Antibody
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (AA 91-140) antibodyWASF1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 Reactivité: Humain, Souris, Rat, Boeuf (Vache) WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (Tyr410) antibodyWASF1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (pTyr125) antibodyWASF1 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-WAS Protein Family, Member 1 (WASF1) (AA 91-140), (pTyr125) antibodyWASF1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1: 1000approx. 1: 5000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- DO NOT FREEZE!
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- WASF1 (WAS Protein Family, Member 1 (WASF1))
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Autre désignation
- WASF1 / WAVE1
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Sujet
- WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases. The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac. The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments. WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes.Synonyms: KIAA0269, SCAR1, Verprolin homology domain-containing protein 1, WASP family protein member 1, WAVE-1, Wiskott-Aldrich syndrome protein family member 1
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Poids moléculaire
- approx. 65 kDa
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ID gène
- 8936
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NCBI Accession
- NP_001020105
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UniProt
- Q92558
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Pathways
- Signalisation RTK, Regulation of Actin Filament Polymerization
Antigène
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